Substance |
Info | Dose |
Warn | Link |
PubMed |
Latest article |
Berberine | 📋 | ✍ | ⛔ | | 38424708 | Berberine attenuates inflammation and oxidative stress and modulates lymphocyte E-NTPDase in acute hyperlipidemia |
Red Yeast Rice | 📋 | ✍ | ⛔ | | 38480501 | Red Yeast Rice and Statin Therapy in Patients with Hypercholesterolemia and the Comorbidities: A Retrospective Cohort Study on Lipid-Lowering Effects and Cardiovascular Outcomes |
Curcumin | 📋 | ✍ | ⛔ | | 38481552 | Curcumin in treatment of hematological cancers: Promises and challenges |
Omega-3 Fatty Acids | 📋 | ✍ | ⛔ | | 38584606 | New approaches to triglyceride reduction: Is there any hope left? |
Vitamin D3 | 📋 | ✍ | ⛔ | | 38536498 | Effect of vitamin D3 supplementation on blood parameters and liver gene expression in female rats |
Vitamin B9 | 📋 | ✍ | ⛔ | | 38649347 | Folic acid supplementation on inflammation and homocysteine in type 2 diabetes mellitus: systematic review and meta-analysis of randomized controlled trials |
Metformin | 📋 | ✍ | ⛔ | | 37975061 | High Dose of Metformin Decreases Susceptibility to Occlusive Arterial Thrombosis in Diabetic Mice |
Cinnamon | 📋 | ✍ | ⛔ | | 37909519 | Effectiveness of cinnamon in the reduction of lipid levels in people with diabetes: a randomized clinical trial |
Mulberry | 📋 | | ⛔ | | 37272629 | Effect of mulberry fruit extract on post-prandial glycemic and insulinemic responses to different rice types: A randomised trial in healthy adults |
Resveratrol | 📋 | ✍ | ⛔ | | 38613119 | Resveratrol Improves Hyperuricemia and Ameliorates Renal Injury by Modulating the Gut Microbiota |
CoQ10 | 📋 | ✍ | ⛔ | | 37375586 | Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial |
Cocoa | 📋 | ✍ | ⛔ | | 38533262 | New light on changes in the number and function of blood platelets stimulated by cocoa and its products |
Vitamin C | 📋 | ✍ | ⛔ | | 38454269 | Successful Treatment with Ascorbic Acid in a Case of Methemoglobinemia Due to Glucose-6-Phosphate Dehydrogenase Deficiency |
Ginseng | 📋 | ✍ | ⛔ | | 37188264 | Hypolipidemic effect and molecular mechanism of ginsenosides: a review based on oxidative stress |
Grape Seed extract | 📋 | ✍ | ⛔ | | 38007734 | Effect of Grape Seed Procyanidins Combined with Allicin on Lipid Levels in Hyperlipidemic Rats |
Anthocyanins | 📋 | ✍ | ⛔ | | 37649528 | Effects of anthocyanin supplementation on blood lipid levels: a systematic review and meta-analysis |
Coconut Oil | 📋 | | ⛔ | | 37893623 | Lipid Profile in Multiple Sclerosis: Functional Capacity and Therapeutic Potential of Its Regulation after Intervention with Epigallocatechin Gallate and Coconut Oil |
Vitamin B12 | 📋 | ✍ | ⛔ | | 38201964 | Hyperhomocysteinemia in Adult Patients: A Treatable Metabolic Condition |
Almond | 📋 | | ⛔ | | 36963852 | Premeal almond load decreases postprandial glycaemia, adiposity and reversed prediabetes to normoglycemia: A randomized controlled trial |
Nigella Sativa | 📋 | ✍ | ⛔ | | 36909699 | A review on hypo-cholesterolemic activity of Nigella sativa seeds and its extracts |
Quercetin | 📋 | ✍ | ⛔ | | 37674537 | Study on Optimal Extraction and Hypoglycemic Effect of Quercetin |
EGCG | 📋 | ✍ | ⛔ | | 37893623 | Lipid Profile in Multiple Sclerosis: Functional Capacity and Therapeutic Potential of Its Regulation after Intervention with Epigallocatechin Gallate and Coconut Oil |
Ginsenosides | 📋 | ✍ | ⛔ | | 38474620 | Ginsenoside Rb1, Compound K and 20(S)-Protopanaxadiol Attenuate High-Fat Diet-Induced Hyperlipidemia in Rats via Modulation of Gut Microbiota and Bile Acid Metabolism |
Pantethine | 📋 | ✍ | ⛔ | | 37194410 | Pantethine ameliorates recognition impairment in a mouse model of Alzheimer's disease by modulating cholesterol content and intestinal flora species |
Fenugreek | 📋 | ✍ | ⛔ | | 36837450 | Effect of Fenugreek on Hyperglycemia: A Systematic Review and Meta-Analysis |
Melatonin | 📋 | ✍ | ⛔ | | 37975141 | Melatonin and probiotic administration ameliorated hyperglycaemia, oxidative stress, and enhanced cytoprotective effect on beta-cells of diabetic rats |
Fish Oil | 📋 | ✍ | ⛔ | | 38317191 | Comparison of fish oil supplements and corn oil effects on serum lipid profile: a systematic review and meta-analysis of randomized controlled trials |
Garlic | 📋 | ✍ | ⛔ | | 38008957 | Synergistic effect of Moringa oleifera and Allium sativum on BMI and lipid profile: A randomized controlled trial |
Walnut | 📋 | | ⛔ | | 38089061 | The antihyperlipidemic effect of a combined supplement of standardized dry extracts of amla ( Emblica officinalis), walnut ( Juglans regia), olive ( Olea europaea) and red yeast rice ( Monascus purpureus) powder: Reduction in circulatory low-density lipoprotein-cholesterol (LDL-C) and remnant cholesterol (RC) levels in patients with hypercholesterolemia |
Bergamot | 📋 | ✍ | ⛔ | | 37732063 | Metabolic and vascular effect of a new standardized bergamot phytocomplex: a three-arm, placebocontrolled, double-blind clinical trial |
Green Tea | 📋 | ✍ | ⛔ | | 38494692 | Effects of coffee and tea on postprandial cardiometabolic risk factors in healthy individuals: a randomized crossover trial |
Argan Oil | 📋 | ✍ | ⛔ | | 34068075 | In Vitro & In Vivo Anti-Hyperglycemic Potential of Saponins Cake and Argan Oil from Argania spinosa |
Magnesium | 📋 | ✍ | ⛔ | | 38228168 | Effects of co-supplementation of chromium and magnesium on metabolic profiles, inflammation, and oxidative stress in impaired glucose tolerance |
Moringa Oleifera | 📋 | ✍ | ⛔ | | 38008957 | Synergistic effect of Moringa oleifera and Allium sativum on BMI and lipid profile: A randomized controlled trial |
Olive Oil | 📋 | ✍ | ⛔ | | 37571288 | The Metabolic and Analytical Changes of Healthy Volunteers upon Intake of Portuguese Extra Virgin Olive Oil: A Comparison Study between Pre- and Post-Intervention |
Reishi Mushrooms | 📋 | ✍ | ⛔ | | 38116485 | Effect of Ganoderma lucidum on serum lipid profiles: A systematic review and meta-analysis on animal studies |
Astaxanthin | 📋 | ✍ | ⛔ | | 37051124 | Effects of Astaxanthin supplementation on selected metabolic parameters, anthropometric indices, Sirtuin1 and TNF-α levels in patients with coronary artery disease: A randomized, double-blind, placebo-controlled clinical trial |
Hesperidin | 📋 | ✍ | ⛔ | | 38577143 | Hesperidin Supplementation Improves Altered PON -1, LDL Oxidation, Inflammatory Response and Hepatic Function in an Experimental Rat Model of Hyperlipidemia |
L-Carnitine | 📋 | ✍ | ⛔ | | 37727632 | The effect of L-carnitine supplementation on lipid profile in adults: an umbrella meta-analysis on interventional meta-analyses |
Ginger | 📋 | ✍ | ⛔ | | 36786398 | Effect of ginger (Zingiber officinale) intake on human serum lipid profile: Systematic review and meta-analysis |
Oats | 📋 | | ⛔ | | 38477294 | Oat protein modulates cholesterol metabolism and improves cardiac systolic function in high fat, high sucrose fed rats |
Spirulina | 📋 | ✍ | ⛔ | | 37263369 | The effect of Spirulina supplementation on lipid profile: GRADE-assessed systematic review and dose-response meta-analysis of data from randomized controlled trials |
Vitamin B6 | 📋 | ✍ | ⛔ | | 38601120 | Preventing hyperhomocysteinemia using vitamin B6 supplementation in Givosiran-treated acute intermittent porphyria: Highlights from a case report and brief literature review |
Apple | 📋 | | ⛔ | | 36811563 | Chronic consumption of probiotics, oats, and apples has differential effects on postprandial bile acid profile and cardiometabolic disease risk markers compared with an isocaloric control (cornflakes): a randomized trial |
Fucoidan | 📋 | ✍ | ⛔ | | 38410655 | Hypolipidemic effect of brown seaweed ( Sargassum crassifolium) extract in vivo (Study of histopathology, mRNA expression, and immunohistochemistry (IHC) with VCAM-1, ICAM-1, and MCP-1 parameters) |
Green Tea Polyphenols | 📋 | ✍ | ⛔ | | 37513933 | The Effects of Green Tea Catechins in Hematological Malignancies |
Hawthorn | 📋 | ✍ | ⛔ | | 38482041 | Efficacy of traditional Chinese medicine containing hawthorn for hyperlipidemia: a systematic review and meta-analysis |
Vitamin B3 | 📋 | ✍ | ⛔ | | 33761625 | The efficacy of niacin supplementation in type 2 diabetes patients: Study protocol of a randomized controlled trial |
Blueberry | 📋 | ✍ | ⛔ | | 35564709 | Effects of Montmorency Tart Cherry and Blueberry Juice on Cardiometabolic and Other Health-Related Outcomes: A Three-Arm Placebo Randomized Controlled Trial |
Ellagic Acid | 📋 | ✍ | ⛔ | | 37153957 | Xanthine oxidase inhibitory kinetics and mechanism of ellagic acid: In vitro, in silico and in vivo studies |
Goji Berry | 📋 | ✍ | ⛔ | | 38628207 | Anthocyanins from Lycium ruthenicum Murray attenuates high-fat diet-induced hypercholesterolemia in ApoE-/- mice are related to the modulation of gut microbiota and the ratio of conjugated to unconjugated bile acids in fecal bile acid profile |
Sea Buckthorn | 📋 | ✍ | ⛔ | | 38007790 | Protective Effect of Sea Buckthorn (Hipphophae Rhamnoides) Extract on Liver Injury Induced by High-Fat Diet in Mice |
Chokeberry | 📋 | ✍ | ⛔ | | 34359511 | Black Chokeberry ( Aronia melanocarpa) Functional Beverages Increase HDL-Cholesterol Levels in Aging Rats |
L-Arginine | 📋 | ✍ | ⛔ | | 36686069 | Arginine for the Treatment of Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes: A Systematic Review |
Lycopene | 📋 | ✍ | ⛔ | | 36422550 | Lycopene Modulates Oxidative Stress and Inflammation in Hypercholesterolemic Rats |
Pomegranate | 📋 | | ⛔ | | 38661445 | Pomegranate supplementation alleviates dyslipidemia and the onset of non-alcoholic fatty liver disease in Wistar rats by shifting microbiota and producing urolithin-like microbial metabolites |
Coffee | 📋 | ✍ | ⛔ | | 37936369 | Coffee Leaf Tea Extracts Improve Hyperuricemia Nephropathy and Its Associated Negative Effect in Gut Microbiota and Amino Acid Metabolism in Rats |
Maitake Mushrooms | 📋 | | ⛔ | | 37193332 | Long-term consumption of different doses of Grifola frondosa affects immunity and metabolism: correlation with intestinal mucosal microbiota and blood lipids |
Orange | 📋 | | ⛔ | | 38257135 | Effect of 100% Orange Juice and a Volume-Matched Sugar-Sweetened Drink on Subjective Appetite, Food Intake, and Glycemic Response in Adults |
Pomegranate Peel extract | 📋 | ✍ | ⛔ | | 37457904 | Effect of Rhodiola rosea Rhizome and Punica granatum Fruit Peel on the Metabolic Processes and Physiological Activity of Rats Fed with Excessively Fat Diet |
Psyllium | 📋 | ✍ | ⛔ | | 38688104 | Plantago consumption significantly reduces total cholesterol and low-density lipoprotein cholesterol in adults: A systematic review and meta-analysis |
Saffron | 📋 | ✍ | ⛔ | | 38207245 | Safety evaluation of saffron extracts in early and established atherosclerotic New Zealand white rabbits |
Star Fuit | 📋 | | ⛔ | | 36814487 | Averrhoa carambola leaves prevent dyslipidemia and oxidative stress in a rat model of poloxamer-407-induced acute hyperlipidemia |
Whey Protein | 📋 | ✍ | ⛔ | | 38076400 | Whey Protein Supplementation and Type 2 Diabetes Mellitus Risk Factors: An Umbrella Systematic Review of Randomized Controlled Trials |
Avocado | 📋 | ✍ | ⛔ | | 37525782 | Effect of Avocado Consumption on Risk Factors of Cardiovascular Diseases: A Systematic Review and Meta-Analysis |
Blackcurrant | 📋 | ✍ | ⛔ | | 37893207 | Blackcurrant Anthocyanins Improve Blood Lipids and Biomarkers of Inflammation and Oxidative Stress in Healthy Women in Menopause Transition without Changing Body Composition |
Coptis Chinensis | 📋 | | ⛔ | | 38677575 | Mechanism of the components compatibility of Scutellariae Radix and Coptidis Rhizoma on mice with hyperlipidemia by regulating the Cyp4a family |
Indian Gooseberry | 📋 | | ⛔ | | 38171388 | Free radical scavenging polyphenols isolated from Phyllanthus niruri L. ameliorates hyperglycemia via SIRT1 induction and GLUT4 translocation in in vitro and in vivo models |
Naringenin | 📋 | ✍ | ⛔ | | 37195720 | Naringenin Prevents Renal Injury in Experimental Hyperuricemia Through Suppressing Xanthine Oxidase, Inflammation, Apoptotic Pathway, DNA Damage, and Activating Antioxidant System |
Rutin | 📋 | ✍ | ⛔ | | 37528147 | Influence of rutin and its combination with metformin on vascular functions in type 1 diabetes |
Vitamin E | 📋 | ✍ | ⛔ | | 38549357 | Effect of vitamin E supplementation on bilirubin levels in infants with hyperbilirubinemia: a double-blind randomized clinical trial |
Capsaicin | 📋 | ✍ | ⛔ | | 36907948 | Enhanced hypoglycemic bioactivity via RAS/Raf-1/MEK/ERK signaling pathway by combining capsaicin and QUERCETIN from chili peppers |
Chlorogenic Acid | 📋 | ✍ | ⛔ | | 38103317 | Chlorogenic acid regulates the expression of NPC1L1 and HMGCR through PXR and SREBP2 signaling pathways and their interactions with HSP90 to maintain cholesterol homeostasis |
Chromium | 📋 | ✍ | ⛔ | | 38228168 | Effects of co-supplementation of chromium and magnesium on metabolic profiles, inflammation, and oxidative stress in impaired glucose tolerance |
Grape | 📋 | | ⛔ | | 37672802 | Concentrated Grape Powder Consumption Modulates Cholesterol Metabolism and Homeostasis in Healthy Subjects |
Luteolin | 📋 | ✍ | ⛔ | | 38026984 | Luteolin inhibits GPVI-mediated platelet activation, oxidative stress, and thrombosis |
Papaya | 📋 | ✍ | ⛔ | | 37457684 | Hypolipidaemic effects of papaya ( Carica papaya L.) juice on rats fed on a high fat and fructose diet |
Pterostilbene | 📋 | ✍ | ⛔ | | 33852294 | Pterostilbene, a Dimethylether Analogue of Resveratrol, Possesses High Potency in the Prevention of Platelet Activation in Humans and the Reduction of Vascular Thrombosis in Mice |
Roselle | 📋 | ✍ | ⛔ | | 36562602 | The Nephroprotective Effects of Hibiscus sabdariffa Leaf and Ellagic Acid in Vitro and in Vivo Models of Hyperuricemic Nephropathy |
Apigenin | 📋 | ✍ | ⛔ | | 36808364 | Apigenin ameliorates hypercholesterolemic-induced kidney injury via modulating renal KIM-1, Fn1, and Nrf2 signaling pathways |
Barley | 📋 | ✍ | ⛔ | | 37940671 | Beneficial glycaemic effects of high-amylose barley bread compared to wheat bread in type 2 diabetes |
Flaxseed | 📋 | ✍ | ⛔ | | 38663513 | Impact of Flaxseed Supplementation on Lipid Profile and Liver Enzymes in Patients with Non-Alcoholic Fatty Liver Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials |
Genistein | 📋 | ✍ | ⛔ | | 38115108 | Identifying the natural products in the treatment of atherosclerosis by increasing HDL-C level based on bioinformatics analysis, molecular docking, and in vitro experiment |
Ginkgo Biloba | 📋 | ✍ | ⛔ | | 36916480 | Effect of Ginkgo biloba extract on pharmacology and pharmacokinetics of atorvastatin in rats with hyperlipidaemia |
Lotus | 📋 | | ⛔ | | 38021260 | Comparison of fresh and browning lotus roots ( Nelumbo nucifera Gaertn.) on modulating cholesterol metabolism via decreasing hepatic cholesterol deposition and increasing fecal bile acid excretion |
Ollive Leaf extract | 📋 | ✍ | ⛔ | | 37375586 | Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial |
Stevia | 📋 | ✍ | ⛔ | | 37677968 | Steviol glycosides from Stevia rebaudiana Bertoni mitigate lipid metabolism abnormalities in diabetes by modulating selected gene expression - An in vivo study |
Thymoquinone | 📋 | | ⛔ | | 37568105 | Protective role of thymoquinone in hyperlipidemia-induced liver injury in LDL-R-/-mice |
Turmeric | 📋 | ✍ | ⛔ | | 38347961 | Curcuma longa extract reduces serum inflammatory markers and postprandial hyperglycemia in healthy but borderline participants with overweight and glycemia in the normal/prediabetes range: a randomized, double-blind, and placebo-controlled trial |
Aloe Vera | 📋 | ✍ | ⛔ | | 36481618 | Aloe vera in diabetic dyslipidemia: Improving blood glucose and lipoprotein levels in pre-clinical and clinical studies |
Food | 📋 | | | | 38137270 | Understanding Hyperuricemia: Pathogenesis, Potential Therapeutic Role of Bioactive Peptides, and Assessing Bioactive Peptide Advantages and Challenges |
Ginger extract | 📋 | ✍ | ⛔ | | 36900554 | The Effect of Ginger ( Zingiber officinale Roscoe) Aqueous Extract on Postprandial Glycemia in Nondiabetic Adults: A Randomized Controlled Trial |
Kiwifruit | 📋 | ✍ | ⛔ | | 35956366 | Dietary Fibre and Organic Acids in Kiwifruit Suppress Glycaemic Response Equally by Delaying Absorption-A Randomised Crossover Human Trial with Parallel Analysis of 13 C-Acetate Uptake |
Phytochemicals | 📋 | | | | 37835351 | Anti-Hyperglycemic Effects of Bioactive Compounds in the Context of the Prevention of Diet-Related Diseases |
Pine Bark | 📋 | ✍ | ⛔ | | 32075228 | An Acute, Placebo-Controlled, Single-Blind, Crossover, Dose-Response, Exploratory Study to Assess the Effects of New Zealand Pine Bark Extract (Enzogenol ®) on Glycaemic Responses in Healthy Participants |
Puerarin | 📋 | ✍ | ⛔ | | 36137324 | Comparison of 3 hyperuricemia mouse models and evaluation of food-derived anti-hyperuricemia compound with spontaneous hyperuricemia mouse model |
Strawberry | 📋 | ✍ | ⛔ | | 37462847 | The Hypoglycemic and Hypolipidemic Effects of Polyphenol-Rich Strawberry Juice on Diabetic Rats |
Zinc | 📋 | ✍ | ⛔ | | 38258780 | The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats |
Aged Garlic | 📋 | ✍ | ⛔ | | 36640154 | Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis |
Astragalus Root | 📋 | ✍ | ⛔ | | 37824046 | Astragalus polysaccharide alleviates polycystic ovary syndrome by reducing insulin resistance and oxidative stress and increasing the diversity of gut microbiota |
Baicalin | 📋 | ✍ | ⛔ | | 38580458 | Baicalin inhibits monosodium urate crystal-induced pyroptosis in renal tubular epithelial cell line through Panx-1/P2X7 pathways: Molecular docking, molecular dynamics, and in vitro experiments |
Bee Propolis | 📋 | ✍ | ⛔ | | 36170859 | A Systematic Review of the Potential Effects of Propolis Extracts on Experimentally-induced Diabetes |
Beta-Glucan | 📋 | ✍ | ⛔ | | 36657917 | The separate effects of whole oats and isolated beta-glucan on lipid profile: A systematic review and meta-analysis of randomized controlled trials |
Catechins | 📋 | | | | 38034724 | Effects of green tea catechin on the blood pressure and lipids in overweight and obese population-a meta-analysis |
Cranberry | 📋 | ✍ | ⛔ | | 38542695 | The Effects of Cranberry Consumption on Glycemic and Lipid Profiles in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
Crocin | 📋 | ✍ | ⛔ | | 38617922 | Modulating effects of crocin on lipids and lipoproteins: Mechanisms and potential benefits |
Evening Primrose Oil | 📋 | ✍ | ⛔ | | 35791734 | Supplementation with omega-3 or omega-6 fatty acids attenuates platelet reactivity in postmenopausal women |
Fisetin | 📋 | ✍ | ⛔ | | 38129008 | Fisetin, a dietary flavonoid, promotes transintestinal cholesterol excretion through the activation of PPARδ |
Guggul | 📋 | ✍ | ⛔ | | 37516016 | In-vivo anti-diabetic and anti-hyperlipidemic effects of natural metabolites from resin of Commiphora mukul and their in-silico to in-vitro target fishing |
Lactobacillus plantarum | 📋 | | ⛔ | | 38015360 | Distinct Microbial Taxa Are Associated with LDL-Cholesterol Reduction after 12 Weeks of Lactobacillus plantarum Intake in Mild Hypercholesterolemia: Results of a Randomized Controlled Study |
Pumpkin | 📋 | | ⛔ | | 35959224 | In Vitro Role of Pumpkin Parts as Pharma-Foods: Antihyperglycemic and Antihyperlipidemic Activities of Pumpkin Peel, Flesh, and Seed Powders, in Alloxan-Induced Diabetic Rats |
Punicalagin | 📋 | ✍ | ⛔ | | 38609050 | Punicalagin attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions |
Selenium | 📋 | ✍ | ⛔ | | 38258780 | The Effect of Selenium, Zinc, and their Combined Supplementation on Cardiometabolic Biomarkers-comparing their Effects in the Energy Restriction and High-fat Diet Methods in Obese Rats |
Shiitake Mushrooms | 📋 | ✍ | ⛔ | | 37803584 | Shiitake polysaccharides acted as a non-competitive inhibitor to α-glucosidase and inhibited glucose transport of digested starch from Caco-2 cells monolayer |
Silymarin | 📋 | ✍ | ⛔ | | 38089157 | Effect of dietary supplementation with a new nutraceutical formulation on cardiometabolic risk factors: a double-blind, placebo-controlled, randomized clinical study |
Andrographis | 📋 | ✍ | ⛔ | | 35095497 | Extracts of Andrographis paniculata (Burm.f.) Nees Leaves Exert Anti-Gout Effects by Lowering Uric Acid Levels and Reducing Monosodium Urate Crystal-Induced Inflammation |
Apple Vinegar | 📋 | ✍ | ⛔ | | 34684574 | The Changes in Endogenous Metabolites in Hyperlipidemic Rats Treated with Herbal Mixture Containing Lemon, Apple Cider, Garlic, Ginger, and Honey |
Artichoke | 📋 | ✍ | ⛔ | | 37732047 | Three arms, double-blind, non-inferiority, randomized clinical study testing the lipid-lowering effect of a novel dietary supplement containing red yeast rice and artichoke extracts compared to Armolipid Plus® and placebo |
Aspirin | 📋 | | ⛔ | | 37294478 | The efficacy of aspirin to inhibit platelet aggregation in patients hospitalised with a severe infection: a multicentre, open-label, randomised controlled trial |
Black Tea | 📋 | ✍ | ⛔ | | 36505232 | Sichuan dark tea improves lipid metabolism and prevents aortic lipid deposition in diet-induced atherosclerosis model rats |
Brazil Nut | 📋 | | ⛔ | | 34156903 | Impact of Brazil Nut ( Bertholletia excelsa, H.B.K.) Supplementation on Body Composition, Blood Pressure, and the Vascular Reactivity of Wistar Rats When Submitted to a Hypersodium Diet |
Camellia | 📋 | | ⛔ | | 36466393 | Combining effect of camellia oil and squalene on hyperlipidemia-induced reproductive damage in male rats |
Ferulic Acid | 📋 | ✍ | ⛔ | | 37634782 | Ferulic acid ameliorates hyperuricemia by regulating xanthine oxidase |
Folate | 📋 | ✍ | ⛔ | | 38201964 | Hyperhomocysteinemia in Adult Patients: A Treatable Metabolic Condition |
Licorice Root | 📋 | ✍ | ⛔ | | 34676570 | Glycyrrhiza glabra alcoholic root extract ameliorates hyperglycemia, hyperlipidemia, and glycation-induced free iron-mediated oxidative reactions |
Medicinal Plants | 📋 | | | | 37193181 | The potential of Chinese medicines in the treatment of hyperuricemia |
Nobiletin | 📋 | ✍ | | | 36906890 | Hypoglycemic effect of NOBILETIN via Gut MICROBIOTA-Metabolism Axis on Hyperglycemic Mice |
Probiotics | 📋 | ✍ | ⛔ | | 37975141 | Melatonin and probiotic administration ameliorated hyperglycaemia, oxidative stress, and enhanced cytoprotective effect on beta-cells of diabetic rats |
Raspberry | 📋 | ✍ | ⛔ | | 38628181 | The effects of raspberry consumption on lipid profile and blood pressure in adults: A systematic review and meta-analysis |
Taurine | 📋 | ✍ | ⛔ | | 38706565 | Untargeted metabolomics based on ultra-high performance liquid chromatography-mass spectrometry/MS reveals the lipid-lowering mechanism of taurine in hyperlipidemia mice |
Vitamin B1 | 📋 | ✍ | ⛔ | | 36256603 | Metolachlor Poisoning with Lactic Acidosis Improved by Thiamine Administration: A Case Report |
Acai Berry | 📋 | ✍ | ⛔ | | 33539952 | Increased acute blood flow induced by the aqueous extract of Euterpe oleracea Mart. fruit pulp in rats in vivo is not related to the direct activation of endothelial cells |
Andrographolide | 📋 | | | | 37987454 | TXNIP-NLRP3-GSDMD axis-mediated inflammation and pyroptosis of islet β-cells is involved in cigarette smoke-induced hyperglycemia, which is alleviated by andrographolide |
Arjuna | 📋 | ✍ | ⛔ | | 34919901 | Arjunolic acid downregulates elevated blood sugar and pro-inflammatory cytokines in streptozotocin (STZ)-nicotinamide induced type 2 diabetic rats |
Astragalosides | 📋 | ✍ | ⛔ | | 36631922 | Astragaloside IV (ASIV) Mediates Endothelial Progenitor Cell (EPC) Exosomal LINC01963 to Inhibit Pyroptosis and Oxidative Stress in High Glucose-impaired Endothelial Cells |
Baicalein | 📋 | ✍ | ⛔ | | 36974463 | Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signaling pathway |
Barberry | 📋 | ✍ | ⛔ | | 35255880 | The effect of barberry (Berberis integerrima) on lipid profile and systemic inflammation in subjects with cardiovascular risk factors: a randomized controlled trial |
Beets | 📋 | ✍ | ⛔ | | 36837811 | Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome |
Betaine | 📋 | ✍ | ⛔ | | 38667581 | Low Dietary Betaine Intake Is Associated with Increased Blood Cholesterol in Mexican Subjects |
Bilberry | 📋 | ✍ | ⛔ | | 36169276 | Phytonutrients of bilberry fruit and saskatoon berry in the prevention and treatment of dyslipidemia |
Burdock | 📋 | | ⛔ | | 35401796 | Saccharides from Arctium lappa L. root reduce platelet activation and thrombus formation in a laser injury thrombosis mouse model |
Chrysanthemum | 📋 | ✍ | ⛔ | | 36677639 | Analysis of Chemical Constituents of Chrysanthemum morifolium Extract and Its Effect on Postprandial Lipid Metabolism in Healthy Adults |
Chrysin | 📋 | ✍ | ⛔ | | 35892244 | Chrysin reduces hypercholesterolemia-mediated atherosclerosis through modulating oxidative stress, microflora, and apoptosis in experimental rats |
Hesperetin | 📋 | | | | 37124197 | Anti-hyperuricemia effect of hesperetin is mediated by inhibiting the activity of xanthine oxidase and promoting excretion of uric acid |
Mangiferin | 📋 | | ⛔ | | 32941163 | Evaluation of efficacy of Bombax ceiba extract and its major constituent, mangiferin in streptozotocin (STZ)-induced diabetic rats |
Micronutrients | 📋 | | ⛔ | | 38145747 | A Historical, Evidence-Based, and Narrative Review on Commonly Used Dietary Supplements in Lipid-Lowering |
Olive Polyphenols | 📋 | | | | 38132869 | Olive Oil Polyphenols Improve HDL Cholesterol and Promote Maintenance of Lipid Metabolism: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
Pistachio | 📋 | ✍ | ⛔ | | 34933637 | Consumption of pistachio nuts positively affects lipid profiles: A systematic review and meta-analysis of randomized controlled trials |
Procyanidins | 📋 | | ⛔ | | 37803795 | Peanut skin procyanidins reduce intestinal glucose transport protein expression, regulate serum metabolites and ameliorate hyperglycemia in diabetic mice |
Pu-erh Tea | 📋 | ✍ | ⛔ | | 33598200 | Hypolipidemic, anti-inflammatory, and anti-atherosclerotic effects of tea before and after microbial fermentation |
Schisandra | 📋 | ✍ | ⛔ | | 38718889 | Petroleum ether extract of Schisandra sphenanthera prevents hyperglycemia and insulin resistance in association with modulation of sweet taste receptors and gut microbiota in T2DM rats |
Sweet Potato | 📋 | | ⛔ | | 37455136 | Diacylated anthocyanins from purple sweet potato ( Ipomoeabatatas L.) attenuate hyperglycemia and hyperuricemia in mice induced by a high-fructose/high-fat diet |
Tomato | 📋 | | ⛔ | | 36118749 | Water-soluble tomato concentrate modulates shear-induced platelet aggregation and blood flow in vitro and in vivo |
Apple Polyphenols | 📋 | | ⛔ | | 32739411 | Apple polyphenol-rich drinks dose-dependently decrease early-phase postprandial glucose concentrations following a high-carbohydrate meal: a randomized controlled trial in healthy adults and in vitro studies |
Basil | 📋 | ✍ | ⛔ | | 35470646 | Ocimum basilicum alleviates blood glucose, lipid profile and iNOS in diabetes gestational rat model |
Cardamom | 📋 | ✍ | ⛔ | | 32359750 | Effect of green cardamom on lipoproteins, glycemic control and anthropometric parameters: A meta-analysis of randomized clinical trials |
Cordyceps | 📋 | ✍ | ⛔ | | 37599693 | Cordyceps cicadae polysaccharides alleviate hyperglycemia by regulating gut microbiota and its mmetabolites in high-fat diet/streptozocin-induced diabetic mice |
Date | 📋 | | ⛔ | | 37333476 | Effect of Ajwa date pits powder ( Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial |
Docosahexaenoic Acid | 📋 | ✍ | ⛔ | | 38680033 | Docosahexaenoic Acid Supplementation for Neonatal Hyperbilirubinemia: A Double-Blind, Randomized Clinical Trial |
Eicosapentaenoic Acid | 📋 | ✍ | ⛔ | | 38382916 | Pleiotropic beneficial cardiometabolic actions of a high-purity eicosapentaenoic acid product in high cardiovascular risk individuals |
Emodin | 📋 | | ⛔ | | 38286356 | Cholesterol-lowering effects of rhubarb free anthraquinones and their mechanism of action |
Fiber | 📋 | ✍ | ⛔ | | 38500805 | Eggs and a Fiber-Rich Diet Are Beneficially Associated with Lipid Levels in Framingham Offspring Study Adults |
Gallic Acid | 📋 | | ⛔ | | 36125096 | Hypouricemic effect of gallic acid, a bioactive compound from Sonneratia apetala leaves and branches, on hyperuricemic mice |
Haritaki | 📋 | ✍ | ⛔ | | 38159820 | The Terminalia chebula Retz extract treats hyperuricemic nephropathy by inhibiting TLR4/MyD88/NF-κB axis |
Mango Leaf | 📋 | | ⛔ | | 31914140 | Aqueous extract from Mangifera indica Linn. (Anacardiaceae) leaves exerts long-term hypoglycemic effect, increases insulin sensitivity and plasma insulin levels on diabetic Wistar rats |
Myrrh | 📋 | ✍ | ⛔ | | 32197395 | Commiphora myrrha Resin Alcoholic Extract Ameliorates High Fat Diet Induced Obesity via Regulation of UCP1 and Adiponectin Proteins Expression in Rats |
Nattokinase | 📋 | ✍ | ⛔ | | 37836525 | The Effect of Nattokinase-Monascus Supplements on Dyslipidemia: A Four-Month Randomized, Double-Blind, Placebo-Controlled Clinical Trial |
Oleuropein | 📋 | | | | 29960113 | The olive constituent oleuropein, as a PPARα agonist, markedly reduces serum triglycerides |
Peanut | 📋 | | ⛔ | | 36782346 | Effects of the polypeptide from peanut meal mixed fermentation on lipid metabolism and intestinal flora of hyperlipidemic mice |
Piperine | 📋 | ✍ | ⛔ | | 38498316 | Piperine Improves Hyperuricemic Nephropathy by Inhibiting URAT1/GLUT9 and the AKT-mTOR Pathway |
Soy | 📋 | ✍ | ⛔ | | 38342411 | Effect of unfermented soy product consumption on blood lipids in postmenopausal women: A systematic review and meta-analysis of randomized controlled trials |
Stinging Nettle | 📋 | ✍ | ⛔ | | 38571539 | Inhibitory effect of stinging nettle (Urtica dioica L.) extract on body weight gain in rats on a high-fat diet |
Tetrahydrocurcumin | 📋 | ✍ | | | 34960104 | Tetrahydrocurcumin Upregulates the Adiponectin-AdipoR Pathway and Improves Insulin Signaling and Pancreatic β-Cell Function in High-Fat Diet/Streptozotocin-Induced Diabetic Obese Mice |
Allicin | 📋 | ✍ | ⛔ | | 38007734 | Effect of Grape Seed Procyanidins Combined with Allicin on Lipid Levels in Hyperlipidemic Rats |
Angelica | 📋 | ✍ | ⛔ | | 34575088 | Antithrombotic Effect of the Ethanol Extract of Angelica gigas Nakai (AGE 232) |
Ashwagandha | 📋 | ✍ | ⛔ | | 26704448 | Evaluating the inhibitory potential of Withania somnifera on platelet aggregation and inflammation enzymes: An in vitro and in silico study |
Blackberry | 📋 | | ⛔ | | 34617546 | Aqueous extracts of lingonberry and blackberry leaves identified by high-content screening beneficially act on cholesterol metabolism |
Chamomile | 📋 | ✍ | ⛔ | | 35293499 | Antioxidant effect of chamomile tea on the salivary glands of streptozotocin-induced diabetic rats |
Coconut | 📋 | | ⛔ | | 38475510 | Coconut ( Cocos nucifera (L.)) Water Improves Glucose Uptake with Concomitant Modulation of Antioxidant and Purinergic Activities in Isolated Rat Psoas Muscles |
Diosmin | 📋 | ✍ | ⛔ | | 35946912 | The Effect of Hesperidin and Diosmin Individually or in Combination on Metabolic Profile and Neuropathy among Diabetic Patients with Metabolic Syndrome: A Randomized Controlled Trial |
Egg | 📋 | | ⛔ | | 38500805 | Eggs and a Fiber-Rich Diet Are Beneficially Associated with Lipid Levels in Framingham Offspring Study Adults |
Flavonoids | 📋 | | ⛔ | | 34925525 | Hypoglycemic Effects of Plant Flavonoids: A Review |
Flaxseed Oil | 📋 | ✍ | ⛔ | | 37960203 | Flaxseed Oil ( Linum usitatissimum) Prevents Cognitive and Motor Damage in Rats with Hyperammonemia |
Frankincense | 📋 | ✍ | ⛔ | | 32550165 | Diabetes Affects Hepatic and Renal Glycoproteins: Effect of Boswellia ovalifoliolata on Glycoproteins Proportions in Diabetes Induced Hepatic and Renal Injury |
Gingerol | 📋 | ✍ | | | 36557312 | Gingerol, a Natural Antioxidant, Attenuates Hyperglycemia and Downstream Complications |
Guava | 📋 | | ⛔ | | 37722234 | Elucidation of anti-hyperglycemic activity of Psidium guajava L. leaves extract on streptozotocin induced neonatal diabetic Long-Evans rats |
Hydroxytyrosol | 📋 | | | | 35565844 | Oral Supplement Containing Hydroxytyrosol and Punicalagin Improves Dyslipidemia in an Adult Population without Co-Adjuvant Treatment: A Randomized, Double-Blind, Controlled and Crossover Trial |
Lipoic Acid | 📋 | ✍ | ⛔ | | 34605276 | Alpha lipoic acid supplementation affects serum lipids in a dose and duration-dependent manner in different health status |
Naringin | 📋 | ✍ | ⛔ | | 36558166 | Extraction of Naringin from Pomelo and Its Therapeutic Potentials against Hyperlipidemia |
Neem | 📋 | ✍ | | | 36521768 | EXPLORING the prophylactic potential of Azadirachta indica leaf extract against dyslipidemia |
NMN | 📋 | ✍ | ⛔ | | 38191197 | Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men |
Onion | 📋 | ✍ | ⛔ | | 38370075 | Quantification of quercetin from red onion ( Allium cepa L.) powder via high-performance liquid chromatography-ultraviolet (HPLC-UV) and its effect on hyperuricemia in male healthy Wistar albino rats |
Polyphenols | 📋 | | | | 36386899 | Polyphenols: Chemoprevention and therapeutic potentials in hematological malignancies |
Quinoa | 📋 | | ⛔ | | 37476690 | Glucolipid metabolism improvement in impaired glucose tolerance subjects consuming a Quinoa-based diet: a randomized parallel clinical trial |
Salidroside | 📋 | | | | 33341055 | Salidroside simultaneously reduces de novo lipogenesis and cholesterol biosynthesis to attenuate atherosclerosis in mice |
Silibinin | 📋 | ✍ | | | 36077379 | Silibinin Suppresses the Hyperlipidemic Effects of the ALK-Tyrosine Kinase Inhibitor Lorlatinib in Hepatic Cells |
Sulforaphane | 📋 | ✍ | ⛔ | | 36371056 | Sulforaphane-driven reprogramming of gut microbiome and metabolome ameliorates the progression of hyperuricemia |
Tangeretin | 📋 | | | | 34684383 | Inhibitory Effect of Tangeretin and Cardamonin on Human Intestinal SGLT1 Activity In Vitro and Blood Glucose Levels in Mice In Vivo |
Tea | 📋 | | | | 36395969 | Research Progress on the Lipid-Lowering and Weight Loss Effects of Tea and the Mechanism of its Functional Components |
Bitter Melon | 📋 | ✍ | ⛔ | | 38107145 | Saponins from Momordica charantia exert hypoglycemic effect in diabetic mice by multiple pathways |
Black Pepper | 📋 | ✍ | ⛔ | | 35936152 | A Comparative Study on Clinical Evaluation of the Hypolipidemic Effects of Allium sativum, Trigonella foenum-graecum, Commiphora mukul, Picrorhiza kurroa, and Piper nigrum: A Pilot Study |
Boswellic Acid | 📋 | ✍ | ⛔ | | 35121344 | Anti-diabetic potential of β-boswellic acid and 11-keto-β-boswellic acid: Mechanistic insights from computational and biochemical approaches |
Chaga Mushrooms | 📋 | ✍ | ⛔ | | 38628208 | Study of active components and mechanisms mediating the hypolipidemic effect of Inonotus obliquus polysaccharides |
Chlorella | 📋 | ✍ | ⛔ | | 35331862 | Effect of supplementation with Chlorella vulgaris on lipid profile in adults: a systematic review and dose-response meta-analysis of randomized controlled trials |
Cinnamaldehyde | 📋 | | | | 35774377 | Cinnamaldehyde Mitigates Atherosclerosis Induced by High-Fat Diet via Modulation of Hyperlipidemia, Oxidative Stress, and Inflammation |
Dandelion | 📋 | ✍ | ⛔ | | 33841825 | Hypoglycemic effect of Taraxacum officinale root extract and its synergism with Radix Astragali extract |
Galangal | 📋 | ✍ | ⛔ | | 35726318 | Synergistic Impacts of Alpinia oxyphylla Seed Extract and Allopurinol against Experimental Hyperuricemia |
Graviola | 📋 | ✍ | ⛔ | | 35076315 | Annona muricata as Possible Alternative in the Treatment of Hyperglycemia: A Systematic Review |
Inulin | 📋 | ✍ | ⛔ | | 34920203 | Pre-meal high-performance inulin supplementation reduce post-prandial glycaemic response in healthy subjects: A repeated single-arm clinical trial |
Kaempferol | 📋 | ✍ | ⛔ | | 35334817 | Coreopsis tinctoria and Its Flavonoids Ameliorate Hyperglycemia in Obese Mice Induced by High-Fat Diet |
Knotweed | 📋 | ✍ | ⛔ | | 36815210 | Ultra-high performance liquid chromatography- quadrupole/ time-of-flight mass spectrometry based lipidomics reveals key lipid molecules as potential therapeutic targets of Polygonum cuspidatum against hyperlipidemia in a hamster model |
Krill Oil | 📋 | ✍ | ⛔ | | 36286433 | Krill Oil Inhibits Cholesterol Synthesis and Stimulated Cholesterol Excretion in Hypercholesterolemic Rats |
Lemon | 📋 | | ⛔ | | 35013789 | Glycemic response, satiety, gastric secretions and emptying after bread consumption with water, tea or lemon juice: a randomized crossover intervention using MRI |
Mango | 📋 | | ⛔ | | 35506190 | Changes in systolic blood pressure, postprandial glucose, and gut microbial composition following mango consumption in individuals with overweight and obesity |
Milk Thistle | 📋 | ✍ | ⛔ | | 37183391 | Impact of Berberine or Berberine Combination Products on Lipoprotein, Triglyceride and Biological Safety Marker Concentrations in Patients with Hyperlipidemia: A Systematic Review and Meta-Analysis |
Persimmon | 📋 | | ⛔ | | 38070815 | Hypoglycemic activity of immature persimmon (Diospyros kaki Thunb.) extracts and its inhibition mechanism for α-amylase and α-glucosidase |
Pumpkin Seed | 📋 | ✍ | ⛔ | | 30055778 | Addition of pooled pumpkin seed to mixed meals reduced postprandial glycemia: a randomized placebo-controlled clinical trial |
Red Sage | 📋 | ✍ | ⛔ | | 38423217 | Elucidating the distinctive regulatory effects and mechanisms of active compounds in Salvia miltiorrhiza Bunge via network pharmacology: Unveiling their roles in the modulation of platelet activation and thrombus formation |
Seaweeds | 📋 | | ⛔ | | 38410655 | Hypolipidemic effect of brown seaweed ( Sargassum crassifolium) extract in vivo (Study of histopathology, mRNA expression, and immunohistochemistry (IHC) with VCAM-1, ICAM-1, and MCP-1 parameters) |
Sesamin | 📋 | ✍ | | | 35396857 | Comparative effects of sesame lignans (sesamin, sesamolin, and sesamol) on oxidative stress and lipid metabolism in steatosis HepG2 cells |
Tongkat Ali | 📋 | ✍ | ⛔ | | 37433989 | Eurycoma longifolia alkaloid components ameliorate hyperuricemic nephropathy via regulating serum uric acid level and relieving inflammatory reaction |
Wine | 📋 | | ⛔ | | 37254366 | Cabernet sauvignon dry red wine ameliorates atherosclerosis in mice by regulating inflammation and endothelial function, activating AMPK phosphorylation, and modulating gut microbiota |
Acetyl-L-Carnitine | 📋 | ✍ | ⛔ | | 34886786 | Ameliorative effect of Acetyl L-carnitine in Alzheimer's Disease via Downregulating of Homocysteine Levels in Hyperhomocysteinemia Induced Cognitive Deficit in mouse model |
Amaranth | 📋 | | ⛔ | | 35796287 | Multigrain porridge possesses superior nutritional quality, its consumption alleviates hyperglycemia, hypercholesterolemia and oxidative stress in obese-diabetic wistar rats |
Antioxidants | 📋 | | ⛔ | | 38487634 | Linear association of compound dietary antioxidant index with hyperlipidemia: a cross-sectional study |
Black Tea Polyphenols | 📋 | | | | 29592809 | Exploring the potential of black tea based flavonoids against hyperlipidemia related disorders |
Buckwheat | 📋 | | ⛔ | | 37655471 | Fagopyrum tataricum ethanol extract ameliorates symptoms of hyperglycemia by regulating gut microbiota in type 2 diabetes mellitus mice |
Chia Seeds | 📋 | | ⛔ | | 37456479 | The Effect of Chia Seeds on High-Density Lipoprotein (HDL) Cholesterol |
Elderberry | 📋 | ✍ | ⛔ | | 30267603 | Long-Term Supplementation of Black Elderberries Promotes Hyperlipidemia, but Reduces Liver Inflammation and Improves HDL Function and Atherosclerotic Plaque Stability in Apolipoprotein E-Knockout Mice |
Eucommia | 📋 | ✍ | ⛔ | | 38518640 | Aqueous extract of fermented Eucommia ulmoides leaves alleviates hyperlipidemia by maintaining gut homeostasis and modulating metabolism in high-fat diet fed rats |
Fig | 📋 | | ⛔ | | 34970629 | Comparison of the Efficiency of Lepidium sativum, Ficus carica, and Punica granatum Methanolic Extracts in Relieving Hyperglycemia and Hyperlipidemia of Streptozotocin-Induced Diabetic Rats |
Fucoxanthin | 📋 | ✍ | ⛔ | | 33645067 | [Effect of fucoxanthin on insulin resistance in obese mice induced by high fat diet] |
Kombucha | 📋 | ✍ | ⛔ | | 37588049 | Kombucha tea as an anti-hyperglycemic agent in humans with diabetes - a randomized controlled pilot investigation |
Licochalcones | 📋 | | | | 30878379 | Enrichment of total flavones and licochalcone A from licorice residues and its hypoglycemic activity |
Lingonberry | 📋 | | ⛔ | | 34617546 | Aqueous extracts of lingonberry and blackberry leaves identified by high-content screening beneficially act on cholesterol metabolism |
Linoleic Acid | 📋 | ✍ | ⛔ | | 37583904 | Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia |
Mangosteen | 📋 | ✍ | ⛔ | | 36634312 | Hypouricemic Actions of the Pericarp of Mangosteen in Vitro and in Vivo |
MSM | 📋 | ✍ | ⛔ | | 35708633 | Methylsulfonylmethane and Sesame Seed Oil Improve Dyslipidemia and Modulate Polyunsaturated Fatty Acid Metabolism in Two Mouse Models of Diabetes |
Nicotinamide | 📋 | ✍ | ⛔ | | 35222903 | Nicotinamide supplementation in diabetic nonalcoholic fatty liver disease patients: randomized controlled trial |
Nuts | 📋 | | ⛔ | | 36771303 | Effects of Nut Consumption on Blood Lipids and Lipoproteins: A Comprehensive Literature Update |
Oleic Acid | 📋 | | ⛔ | | 37817162 | The mechanism of oleic acid inhibiting platelet activation stimulated by collagen |
Peony | 📋 | | ⛔ | | 36908916 | Hypoglycemic and H2O2-induced oxidative injury protective effects and the phytochemical profiles of the ethyl acetate fraction from Radix Paeoniae Alba |
Plum | 📋 | | ⛔ | | 36721717 | Plum supplementation and lipid profile: a systematic review and meta-analysis of randomised controlled trials |
Poria Mushrooms | 📋 | ✍ | | | 38048892 | The anti-hyperlipidemic effects of Poria cocos (Schw.) Wolf extract: Modulating cholesterol homeostasis in hepatocytes via PPARα pathway |
Proanthocyanidins | 📋 | | | | 38391003 | Effect of proanthocyanidins on blood lipids: A systematic review and meta-analysis |
Rhodiola | 📋 | ✍ | ⛔ | | 37457904 | Effect of Rhodiola rosea Rhizome and Punica granatum Fruit Peel on the Metabolic Processes and Physiological Activity of Rats Fed with Excessively Fat Diet |
Rice | 📋 | | ⛔ | | 36948432 | Black rice regulates lipid metabolism, liver injury, oxidative stress and adipose accumulation in high-fat/cholesterol diet mice based on gut microbiota and untargeted metabonomics |
Rosemary Essential Oil | 📋 | ✍ | ⛔ | | 31353725 | Ameliorative impact of cold-pressed Rosmarinus officinalis oil against liver toxicity and genotoxic effects in streptozotocin-induced diabetic rats and their offspring |
Sesame | 📋 | ✍ | ⛔ | | 38316576 | Effect of sesame supplementation on body composition and lipid profile in patients with type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials |
Spikenard | 📋 | ✍ | ⛔ | | 30668444 | Secondary metabolite profiling, cytotoxicity, anti-inflammatory potential and in vitro inhibitory activities of Nardostachys jatamansi on key enzymes linked to hyperglycemia, hypertension and cognitive disorders |
St. Johns Wort | 📋 | ✍ | ⛔ | | 33383372 | Improvements in estrogen deficiency-induced hypercholesterolemia by Hypericum perforatum L. extract are associated with gut microbiota and related metabolites in ovariectomized (OVX) rats |
Vitamin K2 mk-7 | 📋 | ✍ | | | 33574019 | Evaluation of synergistic combination comprising magnesium orotate, menaquinone-7, and cholecalciferol for management of type 2 diabetes and dyslipidemia |
Wormwood | 📋 | ✍ | ⛔ | | 35837139 | Artemisia annua L. Extracts Improved Insulin Resistance via Changing Adiponectin, Leptin and Resistin Production in HFD/STZ Diabetic Mice |
Zeaxanthin | 📋 | ✍ | ⛔ | | 36336325 | The effect of lutein and Zeaxanthine on Dyslipidemia: A meta-analysis study |
Almond Oil | 📋 | | ⛔ | | 31428332 | Co-ingestion of whole almonds and almond oil with carbohydrate suppresses postprandial glycaemia in mice in an insulin-dependent and insulin-independent manner |
Aloe-Emodin | 📋 | | | | 38286356 | Cholesterol-lowering effects of rhubarb free anthraquinones and their mechanism of action |
Anethole | 📋 | | | | 37457161 | Cookies enriched with anethole and secoisolariciresinol diglucoside from flaxseed and fennel seeds improve hypercholesterolemia, lipid profile, and liver functions: A pilot study |
Artemisinin | 📋 | | | | 35293664 | Artemisinin and l-carnitine combination therapy alters the erythrocytes redox status |
Asiatic Acid | 📋 | | | | 26233843 | Asiatic acid mitigates hyperglycemia and reduces islet fibrosis in Goto-Kakizaki rat, a spontaneous type 2 diabetic animal model |
Basil Essential Oil | 📋 | ✍ | ⛔ | | 35591766 | Inhalation of low-dose basil (Ocimum basilicum) essential oil improved cardiovascular health and plasma lipid markers in high fat diet-induced obese rats |
Bay Leaf | 📋 | | ⛔ | | 38597184 | Antihyperlipidemic effect and GC-MS analysis of phytoconstituents from Laurus nobilis essential oil in rat |
Bladderwrack | 📋 | ✍ | ⛔ | | 38667804 | Exploring the Hypocholesterolemic Potential of a Fucus vesiculosus Extract: Omic Insights into Molecular Mechanisms at the Intestinal Level |
Caffeine | 📋 | ✍ | ⛔ | | 35633414 | Comparative and Combined Effects of Epigallocatechin-3-gallate and Caffeine in Reducing Lipid Accumulation in Caenorhabditis elegans |
Cannabidiol | 📋 | ✍ | ⛔ | | 37486107 | Cannabidiol ameliorates inflammatory response partly by AGE-RAGE pathway in diabetic mice |
Carvacrol | 📋 | ✍ | ⛔ | | 38154959 | Carvacrol improves blood lipid and glucose in rats with type 2 diabetes mellitus by regulating short-chain fatty acids and the GPR41/43 pathway |
Cat's Claw | 📋 | ✍ | ⛔ | | 35260150 | GlucoMedix®, an extract of Stevia rebaudiana and Uncaria tomentosa, reduces hyperglycemia, hyperlipidemia, and hypertension in rat models without toxicity: a treatment for metabolic syndrome |
Cherry | 📋 | | ⛔ | | 35564709 | Effects of Montmorency Tart Cherry and Blueberry Juice on Cardiometabolic and Other Health-Related Outcomes: A Three-Arm Placebo Randomized Controlled Trial |
Chickpea | 📋 | | ⛔ | | 37589303 | Antioxidant, anti-inflammatory, hypoglycemic, and anti-hyperglycemic activity of chickpea protein hydrolysates evaluated in BALB-c mice |
Chitosan | 📋 | ✍ | ⛔ | | 35366259 | Chitosan from Crabs ( Scylla serrata) Represses Hyperlipidemia-Induced Hepato-Renal Dysfunctions in Rats: Modulation of CD43 and p53 Expression |
Choline | 📋 | ✍ | ⛔ | | 38172213 | Choline supplementation mitigates effects of bilirubin in cerebellar granule neurons in vitro |
Coriander | 📋 | | ⛔ | | 33477662 | Antioxidant, Anti-Inflammatory and Antidiabetic Proprieties of LC-MS/MS Identified Polyphenols from Coriander Seeds |
Crocetin | 📋 | | | | 38386043 | Comparative pharmacokinetic investigation on crocetin in hyperlipidemia and normal rats after oral administration |
Diallyl Disulfide | 📋 | | | | 37138269 | Diallyl disulfide alleviates hypercholesterolemia induced by a western diet by suppressing endoplasmic reticulum stress in apolipoprotein E-deficient mice |
Dihydromyricetin | 📋 | ✍ | ⛔ | | 35752009 | Dihydromyricetin protects against high glucose-induced endothelial dysfunction: Role of HIF-1α/ROR2/NF-κB |
Dihydroquercetin | 📋 | | | | 34698101 | Antidiabetic Effect of Taxifolin in Cultured L6 Myotubes and Type 2 Diabetic Model KK-A y/Ta Mice with Hyperglycemia and Hyperuricemia |
Dioscin | 📋 | | | | 36468521 | Integrative metabolomics and network pharmacology to study the mechanism of dioscin on hyperuricemia |
Eugenol | 📋 | | | | 38396774 | Eugenol Suppresses Platelet Activation and Mitigates Pulmonary Thromboembolism in Humans and Murine Models |
Fennel | 📋 | ✍ | ⛔ | | 37457161 | Cookies enriched with anethole and secoisolariciresinol diglucoside from flaxseed and fennel seeds improve hypercholesterolemia, lipid profile, and liver functions: A pilot study |
Fo-Ti Root | 📋 | ✍ | ⛔ | | 33292335 | Systemic elucidation on the potential bioactive compounds and hypoglycemic mechanism of Polygonum multiflorum based on network pharmacology |
Formononetin | 📋 | | | | 33761143 | Effects of isoflavone-rich red clover extract on blood glucose level: A randomized, double-blind, placebo-controlled trial |
Gardenia | 📋 | | ⛔ | | 35964948 | Antidiabetic and antioxidant potential of Gardenia latifolia in type-2 diabetic rats fed with high-fat diet plus low-dose streptozotocin |
Grapefruit extract | 📋 | ✍ | ⛔ | | 25003704 | Modulation of hyperglycemia and TNFα-mediated inflammation by helichrysum and grapefruit extracts in diabetic db/db mice |
Gymnema Sylvestre | 📋 | ✍ | ⛔ | | 38137721 | Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial |
Haskap | 📋 | | | | 34439452 | Antioxidant Effect of Lonicera caerulea L. in the Cardiovascular System of Obese Zucker Rats |
Hazelnut | 📋 | | ⛔ | | 38043651 | Effects of hazelnut soluble dietary fiber on lipid-lowering and gut microbiota in high-fat-diet-fed rats |
Helichrysum | 📋 | | ⛔ | | 35011387 | In Vitro Evaluation of the Anti-Diabetic Potential of Aqueous Acetone Helichrysum petiolare Extract (AAHPE) with Molecular Docking Relevance in Diabetes Mellitus |
Honey | 📋 | ✍ | ⛔ | | 36379223 | Effect of honey on cardiometabolic risk factors: a systematic review and meta-analysis |
Icaritin | 📋 | | | | 38224965 | Icaritin sensitizes thrombin- and TxA2-induced platelet activation and promotes hemostasis via enhancing PLCγ2-PKC signaling pathways |
Isoflavones | 📋 | ✍ | ⛔ | | 38569436 | Dietary isoflavone intake is inversely associated with remnant cholesterol in US adults: A cross-sectional study |
Isoliquiritigenin | 📋 | | | | 37082661 | The inhibitory effect of isoliquiritigenin on human platelets in vitro |
Jujube | 📋 | | ⛔ | | 35783519 | Jujuboside A Ameliorates Myocardial Apoptosis and Inflammation in Rats with Coronary Heart Disease by Inhibiting PPAR- α Signaling Pathway |
Kacip Fatimah | 📋 | ✍ | ⛔ | | 32256360 | Anti-hyperuricemic and Anti-inflammatory Effects of Marantodes pumilum as Potential Treatment for Gout |
Kudzu Root | 📋 | ✍ | ⛔ | | 32361558 | Puerarin Ameliorates Hyperglycemia in HFD Diabetic Mice by Promoting β-Cell Neogenesis via GLP-1R Signaling Activation |
L-Glutamine | 📋 | ✍ | ⛔ | | 36125865 | Coadministration of L-alanine and L-glutamine ameliorate blood glucose levels, biochemical indices and histological features in alloxan-induced diabetic rats |
Lavender | 📋 | ✍ | ⛔ | | 34959301 | Antihyperglycemic Effect of Lavandula pedunculata: In Vivo, In Vitro and Ex Vivo Approaches |
Lemon Balm | 📋 | ✍ | ⛔ | | 38575930 | Effects of Melissa officinalis (lemon balm) consumption on serum lipid profile: a meta-analysis of randomized controlled trials |
Lemon Balm Essential Oil | 📋 | ✍ | ⛔ | | 22279139 | Melissa officinalis essential oil reduces plasma triglycerides in human apolipoprotein E2 transgenic mice by inhibiting sterol regulatory element-binding protein-1c-dependent fatty acid synthesis |
Loquat | 📋 | ✍ | ⛔ | | 37498560 | Polyphenol-rich extract from loquat fruit peel prevents hyperlipidemia and hepato-nephrotoxicity in mice: in vivo study and in silico prediction of possible mechanisms involving identified polyphenols and/or their circulating metabolites |
Lutein | 📋 | ✍ | ⛔ | | 36336325 | The effect of lutein and Zeaxanthine on Dyslipidemia: A meta-analysis study |
Myricetin | 📋 | | ⛔ | | 37767484 | Myricetin as a promising inhibitor of platelet fibrinogen receptor in humans |
Myrtle | 📋 | ✍ | ⛔ | | 37566463 | Myrtle Berries Seeds Prevent Dyslipidemia, Inflammation, and Excessive Cardiac Reactive Oxygen Species Production in Response to High-Fat Diet-Induced Obesity |
N-Acetyl Cysteine | 📋 | ✍ | ⛔ | | 35326096 | N-Acetylcysteine Inhibits Platelet Function through the Regeneration of the Non-Oxidative Form of Albumin |
Noni | 📋 | | ⛔ | | 37426193 | Characterizations of microRNAs involved in the molecular mechanisms underlying the therapeutic effects of noni ( Morinda citrifolia L.) fruit juice on hyperuricemia in mice |
Okra | 📋 | | ⛔ | | 37507536 | Clinical efficacy and safety of okra (Abelmoschus esculentus (L.) Moench) in type 2 diabetic patients: a randomized, double-blind, placebo-controlled, clinical trial |
Oyster Mushrooms | 📋 | | ⛔ | | 38472823 | Exploring Therapeutic Potential of Pleurotus ostreatus and Agaricus bisporus Mushrooms against Hyperlipidemia and Oxidative Stress Using Animal Model |
Pecan | 📋 | | ⛔ | | 36822079 | Pecan-enriched diet improves cholesterol profiles and enhances postprandial microvascular reactivity in older adults |
Perilla | 📋 | ✍ | | | 38435751 | Identification of inhibitors from a functional food-based plant Perillae Folium against hyperuricemia via metabolomics profiling, network pharmacology and all-atom molecular dynamics simulations |
Phytosterols | 📋 | | | | 37960208 | The Effect of Dietary Supplementation with Plant Sterols on Total and LDL-Cholesterol in Plasma Is Affected by Adherence to Mediterranean Diet: Insights from the DESCO Randomized Clinical Study |
Polydatin | 📋 | ✍ | | | 38323270 | Polydatin ameliorates low-density lipoprotein cholesterol and lipid metabolism by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9) in triple-negative breast cancer with hyperlipidemia |
Potato | 📋 | | ⛔ | | 36250845 | Clinical Efficacy of Potato Extract for Alleviating Chemoradiotherapy-Related Leukopenia: a Randomized, Single-Blind, Placebo-Controlled Trial |
Prickly Pear | 📋 | | ⛔ | | 36363518 | Does Opuntia ficus-indica Juice Supplementation Improve Biochemical and Cardiovascular Response to a 6-Minute Walk Test in Type 2 Diabetic Patients? |
PUFA | 📋 | | | | 38613089 | Improvement in Visceral Adipose Tissue and LDL Cholesterol by High PUFA Intake: 1-Year Results of the NutriAct Trial |
Rapamycin | 📋 | ✍ | | | 36674739 | Effect of Sirolimus/Metformin Co-Treatment on Hyperglycemia and Cellular Respiration in BALB/c Mice |
Rapeseed Oil | 📋 | ✍ | | | 37740067 | Effects of rapeseed oil on body composition and glucolipid metabolism in people with obesity and overweight: a systematic review and meta-analysis |
Red Clover | 📋 | ✍ | ⛔ | | 33761143 | Effects of isoflavone-rich red clover extract on blood glucose level: A randomized, double-blind, placebo-controlled trial |
Sage | 📋 | ✍ | ⛔ | | 30228801 | The Effect of Short-Toothed and Dalmatian Sage Extracts on Platelet Aggregation |
Sesamol | 📋 | | | | 37110801 | Hypolipidemic and Anti-Atherogenic Effects of Sesamol and Possible Mechanisms of Action: A Comprehensive Review |
Skullcap | 📋 | ✍ | ⛔ | | 38677575 | Mechanism of the components compatibility of Scutellariae Radix and Coptidis Rhizoma on mice with hyperlipidemia by regulating the Cyp4a family |
Soy Protein | 📋 | ✍ | ⛔ | | 38174000 | Protein supplementation: the double-edged sword |
Tannic Acid | 📋 | ✍ | ⛔ | | 34967286 | Dietary Intake of Hydrolyzable Tannins and Condensed Tannins to Regulate Lipid Metabolism |
Trans-Resveratrol | 📋 | | | | 34999386 | Comprehensive assessment of the effectiveness of l-carnitine and transresveratrol in rats with diet-induced obesity |
Tribulus Terrestris | 📋 | ✍ | ⛔ | | 27840471 | Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus |
TUDCA | 📋 | ✍ | ⛔ | | 37687178 | Metabolomics and Lipidomics Study Unveils the Impact of Tauroursodeoxycholic Acid on Hyperlipidemic Mice |
Ursolic Acid | 📋 | ✍ | ⛔ | | 35671633 | Ursolic acid inhibits the cholesterol biosynthesis and alleviates high fat diet-induced hypercholesterolemia via irreversible inhibition of HMGCS1 in vivo |
Vitamin B Complex | 📋 | | ⛔ | | 37637782 | The Effects of Vitamin B-Complex Supplementation on Serum Homocysteine Levels and Migraine Severity in Children A Randomized Controlled Trial |
Vitamin K2 | 📋 | ✍ | ⛔ | | 36696048 | Co-supplementation of Vitamin K2 and Selenium Synergistically Improves Metabolic Status and Reduces Cardiovascular Risk Markers in Dyslipidemic Rabbits |
Withaferin A | 📋 | | | | 35734936 | Modulatory action of withaferin-A on oxidative damage through regulation of inflammatory mediators and apoptosis via PI3K/AKT signaling pathway in high cholesterol-induced atherosclerosis in experimental rats |
Yam | 📋 | | | | 38613011 | A Comparative Analysis between Whole Chinese Yam and Peeled Chinese Yam: Their Hypolipidemic Effects via Modulation of Gut Microbiome in High-Fat Diet-Fed Mice |
Alpha-Linolenic Acid | 📋 | ✍ | ⛔ | | 35107625 | Peony seed oil decreases plasma cholesterol and favorably modulates gut microbiota in hypercholesterolemic hamsters |
Ashitaba | 📋 | ✍ | ⛔ | | 36235163 | Assessment of the Hypoglycemic and Hypolipidemic Activity of Flavonoid-Rich Extract from Angelica keiskei |
Asparagus | 📋 | | ⛔ | | 36313282 | Asparagus cochinchinensis alleviates disturbances of lipid metabolism and gut microbiota in high-fat diet-induced obesity mice |
Atractylodes | 📋 | ✍ | ⛔ | | 38560167 | The anti-hyperlipidemia effect of Atractylodes macrocephala Rhizome increased HDL via reverse cholesterol transfer |
Avocado Oil | 📋 | | ⛔ | | 30051518 | Effect of virgin avocado oil on diet-induced hypercholesterolemia in rats via 1 H NMR-based metabolomics approach |
Bamboo | 📋 | ✍ | ⛔ | | 36712536 | Comparison of physicochemical and in vitro hypoglycemic activity of bamboo shoot dietary fibers from different regions of Yunnan |
Banana | 📋 | | ⛔ | | 36321066 | Estimation of Platelet Count and Bleeding Time of Mice Treated with Musa paradisiaca var. sapientum (L.) Kuntze Extract |
BCAA | 📋 | ✍ | ⛔ | | 35830259 | Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH |
Bean | 📋 | | ⛔ | | 37960148 | Minimal Effective Dose of Beans Required to Elicit a Significantly Lower Glycemic Response Than Commonly Consumed Starchy Foods: Predictions Based on In Vitro Digestion and Carbohydrate Analysis |
Beer | 📋 | | | | 37402233 | Effect of moderate beer consumption (with and without ethanol) on cardiovascular health in postmenopausal women |
Biochanin A | 📋 | | | | 34276221 | Biochanin A Regulates Cholesterol Metabolism Further Delays the Progression of Nonalcoholic Fatty Liver Disease |
Bromelain | 📋 | ✍ | ⛔ | | 37749825 | Protective effect of bromelain on some metabolic enzyme activities in tyloxapol-induced hyperlipidemic rats |
Butyrate | 📋 | | ⛔ | | 36948133 | Protective effect of sodium butyrate on intestinal barrier damage and uric acid reduction in hyperuricemia mice |
Cabbage | 📋 | | ⛔ | | 36866218 | The protective effect of red cabbage on water-soluble fractions of spent crankcase oil-induced alterations in lipid function biomarkers and atherogenic indices in male Albino rats |
Caffeic Acid | 📋 | ✍ | ⛔ | | 36979705 | Potential of Caffeic Acid and 10-Dehydrogingerdione as Lipid Regulators Relevant to Their Inhibitory Effect on miR-122 and ATP Citrate Lyase Activity in Diabetic Hyperlipidemic Rats |
Calcium | 📋 | ✍ | ⛔ | | 35623880 | Urate-lowering effect of calcium supplementation: Analyses of a randomized controlled trial |
Carotenoids | 📋 | ✍ | ⛔ | | 35571897 | Effects of Oral Carotenoids on Oxidative Stress: A Systematic Review and Meta-Analysis of Studies in the Recent 20 Years |
Cashew | 📋 | | ⛔ | | 36235503 | Anacardium occidentale Bark as an Antidiabetic Agent |
Celery | 📋 | | ⛔ | | 35536382 | Safety evaluation and biochemical efficacy of celery seed extract (Apium Graveolens) capsules in hypertensive patients: a randomized, triple-blind, placebo-controlled, cross-over, clinical trial |
Chicory | 📋 | ✍ | ⛔ | | 35228184 | A randomized controlled trial on albino rats treated with chicory plant to improve liver efficiency |
Citicoline | 📋 | ✍ | ⛔ | | 31371071 | A novel approach in the management of hyperhomocysteinemia |
Citrus Fruits | 📋 | | ⛔ | | 35237168 | Citrus Extract as a Perspective for the Control of Dyslipidemia: A Systematic Review With Meta-Analysis From Animal Models to Human Studies |
Coconut Protein | 📋 | | | | 15274481 | Influence of Coconut Kernel Protein on Lipid Metabolism in Alcohol Fed Rats |
Copper | 📋 | ✍ | ⛔ | | 7770185 | Neutropenia Caused by Copper Deficiency: Possible Mechanisms of Action |
Cordycepin | 📋 | | | | 37634411 | Pharmacological and therapeutic potentials of cordycepin in hematological malignancies |
Corn Silk | 📋 | ✍ | ⛔ | | 37294890 | Corn Silk Flavonoids Ameliorate Hyperuricemia via PI3K/AKT/NF-κB Pathway |
Cornus | 📋 | | | | 35781421 | Protective effects of corni fructus extract in mice with potassium oxonate-induced hyperuricemia |
Cyanidin | 📋 | ✍ | | | 35357376 | Antihyperglycemic effect of an anthocyanin, cyanidin-3- O-glucoside, is achieved by regulating GLUT-1 via the Wnt/β-catenin-WISP1 signaling pathway |
Daidzein | 📋 | ✍ | ⛔ | | 37569361 | Daidzein Inhibits Human Platelet Activation by Downregulating Thromboxane A2 Production and Granule Release, Regardless of COX-1 Activity |
Diosgenin | 📋 | | | | 34552341 | The Effects of Diosgenin on Hypolipidemia and Its Underlying Mechanism: A Review |
Diosmetin | 📋 | | | | 35164411 | Flavonoids: Antiplatelet Effect as Inhibitors of COX-1 |
Echinacea | 📋 | ✍ | ⛔ | | 28061036 | Antioxidant, Antidiabetic, and Antihypertensive Properties of Echinacea Purpurea Flower Extract and Caffeic Acid Derivatives Using In Vitro Models |
Forskolin | 📋 | ✍ | ⛔ | | 34104650 | Synergetic Action of Forskolin and Mevastatin Induce Normalization of Lipids Profile in Dyslipidemic Rats through Adenosine Monophosphate Kinase Upregulation |
Garlic Oil | 📋 | | ⛔ | | 35959265 | Garlic oil alleviates high triglyceride levels in alcohol-exposed rats by inhibiting liver oxidative stress and regulating the intestinal barrier and intestinal flora |
Ginkgolides | 📋 | | | | 25223809 | Ginkgolide B inhibits platelet release by blocking Syk and p38 MAPK phosphorylation in thrombin-stimulated platelets |
Glabridin | 📋 | | | | 36232674 | Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice |
Gotu Kola | 📋 | ✍ | ⛔ | | 32526339 | Lei-gong-gen formula granule attenuates hyperlipidemia in rats via cGMP-PKG signaling pathway |
Grapefruit | 📋 | | ⛔ | | 27134462 | Antihyperlipidemic effects of Citrus sinensis, Citrus paradisi, and their combinations |
Guggulsterone | 📋 | | | | 38089157 | Effect of dietary supplementation with a new nutraceutical formulation on cardiometabolic risk factors: a double-blind, placebo-controlled, randomized clinical study |
Holy Basil | 📋 | ✍ | ⛔ | | 25646044 | Antidyslipidemic Effect of Ocimum sanctum Leaf Extract in Streptozotocin Induced Diabetic Rats |
Icariin | 📋 | ✍ | | | 34906049 | AMPK/PGC-1α/GLUT4-Mediated Effect of Icariin on Hyperlipidemia-Induced Non-Alcoholic Fatty Liver Disease and Lipid Metabolism Disorder in Mice |
Indian Barberry | 📋 | ✍ | ⛔ | | 31784970 | The Effects of a Fixed Combination of Berberis aristata and Silybum marianum on Dyslipidaemia - A Meta-analysis and Systematic Review |
Isoquercitrin | 📋 | | | | 34626776 | Mulberry leaves ameliorate diabetes via regulating metabolic profiling and AGEs/RAGE and p38 MAPK/NF-κB pathway |
L-Alanine | 📋 | ✍ | ⛔ | | 36125865 | Coadministration of L-alanine and L-glutamine ameliorate blood glucose levels, biochemical indices and histological features in alloxan-induced diabetic rats |
L-Carnosine | 📋 | ✍ | ⛔ | | 36808356 | Antihyperlipidemic potential of dietary supplementation with carnosine in high-fat diet-fed rats |
Lauric Acid | 📋 | ✍ | | | 37211320 | Lauric acid improves hormonal profiles, antioxidant properties, sperm quality and histomorphometric changes in testis and epididymis of streptozotocin-induced diabetic infertility rats |
Lemon Verbena | 📋 | | ⛔ | | 32520695 | Antihyperglycemic and Antihyperlipidemic Effects of Lippia citriodora in Rats |
Lentil | 📋 | | ⛔ | | 38337705 | Twelve Weeks of Daily Lentil Consumption Improves Fasting Cholesterol and Postprandial Glucose and Inflammatory Responses-A Randomized Clinical Trial |
Ligustilide | 📋 | | | | 37579692 | Ligustilide covalently binds to Cys129 of HMGCS1 to ameliorate dyslipidemia |
Lychee | 📋 | | ⛔ | | 34874786 | Chemical Characterization and Evaluation of the Antihyperglycemic Effect of Lychee ( Litchi chinensis Sonn.) cv. Brewster |
Nicotinamide Riboside | 📋 | ✍ | ⛔ | | 30849366 | The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance |
Nuciferine | 📋 | | | | 37186242 | Nuciferine blocks MIB2-mediated CARD6 polyubiquitination and degradation in the amelioration of high fructose-induced liver lipid accumulation |
Nutmeg | 📋 | ✍ | ⛔ | | 35275149 | Phenylpropanoids and neolignans isolated from Myristica fragrans enhance glucose uptake in myotubes |
Oolong Tea | 📋 | | ⛔ | | 29419789 | Aged Oolong Tea Reduces High-Fat Diet-Induced Fat Accumulation and Dyslipidemia by Regulating the AMPK/ACC Signaling Pathway |
Oregano | 📋 | ✍ | ⛔ | | 34647501 | Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats |
Paeoniflorin | 📋 | | | | 36081948 | Paeoniflorin alleviates liver injury in hypercholesterolemic rats through the ROCK/AMPK pathway |
Pineapple | 📋 | ✍ | ⛔ | | 36062986 | Pineapple fruit improves vascular endothelial dysfunction, hepatic steatosis, and cholesterol metabolism in rats fed a high-cholesterol diet |
Pomegranate Seed extract | 📋 | | ⛔ | | 31117552 | Hypocholesterolemic Effects of Expeller-Pressed and Solvent-Extracted Fruit Seed Oils and Defatted Pomegranate Seed Meals |
Prebiotics | 📋 | ✍ | ⛔ | | 36034697 | Gut microbiota remodeling: A promising therapeutic strategy to confront hyperuricemia and gout |
Pumpkin Seed Oil | 📋 | ✍ | ⛔ | | 26405765 | Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil |
Quercitrin | 📋 | | | | 33076582 | Quercitrin Ameliorates Hyperlipidemia and Hepatic Steatosis in Ovariectomized Mice |
Rosehip | 📋 | ✍ | ⛔ | | 38283449 | Effects of Daily Intake of Rosehip Extract on Low-Density Lipoprotein Cholesterol and Blood Glucose Levels: A Systematic Review |
Rosemary | 📋 | ✍ | ⛔ | | 32158154 | Hypoglycemic efficacy of Rosmarinus officinalis and/or Ocimum basilicum leaves powder as a promising clinico-nutritional management tool for diabetes mellitus in Rottweiler dogs |
Rosmarinic Acid | 📋 | ✍ | | | 35687823 | Rosmarinic Acid Inhibits Platelet Aggregation and Neointimal Hyperplasia In Vivo and Vascular Smooth Muscle Cell Dedifferentiation, Proliferation, and Migration In Vitro via Activation of the Keap1-Nrf2-ARE Antioxidant System |
Royal Jelly | 📋 | ✍ | ⛔ | | 35325025 | Royal jelly fatty acids downregulate ANGPTL8 expression through the decrease in HNF4α protein in human hepatoma HepG2 cells |
Sage Essential Oil | 📋 | | ⛔ | | 32010989 | The protective effects of Salvia officinalis essential oil compared to simvastatin against hyperlipidemia, liver, and kidney injuries in mice submitted to a high-fat diet |
Salt | 📋 | | ⛔ | | 33524391 | Dietary sodium restriction alters muscle lipidomics that relates to insulin resistance in mice |
Saw Palmetto | 📋 | ✍ | ⛔ | | 34161166 | Standardized Saw Palmetto Extract Directly and Indirectly Affects Testosterone Biosynthesis and Spermatogenesis |
Sesame Oil | 📋 | | ⛔ | | 35708633 | Methylsulfonylmethane and Sesame Seed Oil Improve Dyslipidemia and Modulate Polyunsaturated Fatty Acid Metabolism in Two Mouse Models of Diabetes |
Shea | 📋 | | ⛔ | | 33364595 | Hypoglycemic, antidyslipidemic and antioxydant effects of Vitellaria paradoxa barks extract on high-fat diet and streptozotocin-induced type 2 diabetes rats |
Shogaol | 📋 | | | | 30805033 | Beneficial effects of 6-shogaol on hyperglycemia, islet morphology and apoptosis in some tissues of streptozotocin-induced diabetic mice |
Soy Isoflavones | 📋 | ✍ | ⛔ | | 34444691 | Effects of Soy Protein Containing of Isoflavones and Isoflavones Extract on Plasma Lipid Profile in Postmenopausal Women as a Potential Prevention Factor in Cardiovascular Diseases: Systematic Review and Meta-Analysis of Randomized Controlled Trials |
Spices | 📋 | | | | 32211803 | Spices in a High-Saturated-Fat, High-Carbohydrate Meal Reduce Postprandial Proinflammatory Cytokine Secretion in Men with Overweight or Obesity: A 3-Period, Crossover, Randomized Controlled Trial |
Star Anise | 📋 | ✍ | ⛔ | | 30700011 | Hypolipogenic Effect of Shikimic Acid Via Inhibition of MID1IP1 and Phosphorylation of AMPK/ACC |
Tanshinone | 📋 | | | | 34804370 | Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer |
Theabrownins | 📋 | | | | 35088787 | Theabrownin-targeted regulation of intestinal microorganisms to improve glucose and lipid metabolism in Goto-Kakizaki rats |
Theaflavins | 📋 | ✍ | | | 38550892 | Potential anti-hyperglycemic activity of black tea theaflavins through inhibiting α-amylase |
Theobromine | 📋 | ✍ | ⛔ | | 25869509 | Effects of high flavanol dark chocolate on cardiovascular function and platelet aggregation |
Thyme | 📋 | ✍ | ⛔ | | 33995021 | Chemical Composition, Antioxidant Potential, and Blood Glucose Lowering Effect of Aqueous Extract and Essential Oil of Thymus Serrulatus Hochst. Ex Benth |
Trehalose | 📋 | | ⛔ | | 33715524 | A head-to-head comparison review of biological and toxicological studies of isomaltulose, d-tagatose, and trehalose on glycemic control |
White Mushrooms | 📋 | | ⛔ | | 38472823 | Exploring Therapeutic Potential of Pleurotus ostreatus and Agaricus bisporus Mushrooms against Hyperlipidemia and Oxidative Stress Using Animal Model |
Wogonin | 📋 | ✍ | ⛔ | | 34711151 | Wogonin and alleviation of hyperglycemia via inhibition of DAG mediated PKC expression. A brief insight |
Yogurt | 📋 | | ⛔ | | 36484237 | The ability of yoghurt supplemented with dietary fibers or brans extracted from wheat or rice to reduce serum lipids and enhance liver function in male hypercholesterolemic rats |
Yohimbine | 📋 | ✍ | | | 34345380 | Effects of intraperitoneal and intracerebroventricular injection of cinnamaldehyde and yohimbine on blood glucose and serum insulin concentrations in ketamine-xylazine induced acute hyperglycemia |
Alfalfa | 📋 | | ⛔ | | 31210545 | Effects of estrogen deficiency on liver function and uterine development: assessments of Medicago sativa's activities as estrogenic, anti-lipidemic, and antioxidant agents using an ovariectomized mouse model |
Anise | 📋 | ✍ | ⛔ | | 31724151 | Aqueous anise extract alleviated the pancreatic changes in streptozotocin-induced diabetic rat model via modulation of hyperglycaemia, oxidative stress, apoptosis and autophagy: a biochemical, histological and immunohistochemical study |
Anthocyanidins | 📋 | | | | 31279126 | Chemical Compositions and α-Glucosidase Inhibitory Effects of Anthocyanidins From Blueberry, Blackcurrant and Blue Honeysuckle Fruits |
Apricot Kernels | 📋 | ✍ | ⛔ | | 35055679 | Phytonutrients of Bitter Apricot Seeds Modulate Human Lipid Profile and LDL Subfractions in Adults with Elevated Cholesterol Levels |
Arctigenin | 📋 | | | | 32707441 | Arctigenin attenuates platelet activation and clot retraction by regulation of thromboxane A2 synthesis and cAMP pathway |
Asafoetida | 📋 | ✍ | ⛔ | | 30471513 | Antidiabetic and antihyperlipidemic effects of ethanolic Ferula assa-foetida oleo-gum-resin extract in streptozotocin-induced diabetic wistar rats |
Bacopa Monnieri | 📋 | ✍ | ⛔ | | 38380214 | Analyzing the Antihyperglycemic Effect of Cissus quadrangularis and Bacopa monnieri on 3T3-L1 Cell Lines |
Bee Pollen | 📋 | ✍ | ⛔ | | 33288184 | Effect of antioxidant-rich propolis and bee pollen extracts against D-glucose induced type 2 diabetes in rats |
Bee Venom | 📋 | ✍ | ⛔ | | 33443641 | Phospholipase A2 enzyme from the venom of Egyptian honey bee Apis mellifera lamarckii with anti-platelet aggregation and anti-coagulation activities |
Bergamot Essential Oil | 📋 | ✍ | ⛔ | | 30501605 | Hypoglycemic and Hypolipemic Effects of a New Lecithin Formulation of Bergamot Polyphenolic Fraction: A Double Blind, Randomized, Placebo- Controlled Study |
Berries | 📋 | | | | 23365108 | Berries reduce postprandial insulin responses to wheat and rye breads in healthy women |
Beta-Sitosterol | 📋 | ✍ | ⛔ | | 24364088 | [Addition of pomegranate juice to statin inhibits cholesterol accumulation in macrophages: protective role for the phytosterol beta-sitosterol and for the polyphenolic antioxidant punicalagin] |
Betulinic Acid | 📋 | | | | 35458714 | Binding Interaction of Betulinic Acid to α-Glucosidase and Its Alleviation on Postprandial Hyperglycemia |
Broccoli | 📋 | | ⛔ | | 35465108 | Brassica oleracea Extracts Prevent Hyperglycemia in Type 2 Diabetes Mellitus |
Calycosin | 📋 | | | | 35724482 | Calycosin alleviates hyperbilirubin nerve injury in Ugt1 -/- mice by inhibiting oxidative stress, apoptosis, and mitochondrial function |
Cantaloupe | 📋 | | ⛔ | | 36418190 | Cucumis melo seed oil: Agro-food by-product with natural anti-hyperlipidemic potential |
CAPE | 📋 | | | | 35714456 | Caffeic acid phenethyl ester alleviated hypouricemia in hyperuricemic mice through inhibiting XOD and up-regulating OAT3 |
Capsanthin | 📋 | | | | 35892680 | Capsanthin Inhibits Atherosclerotic Plaque Formation and Vascular Inflammation in ApoE -/- Mice |
Cardamonin | 📋 | | | | 34684383 | Inhibitory Effect of Tangeretin and Cardamonin on Human Intestinal SGLT1 Activity In Vitro and Blood Glucose Levels in Mice In Vivo |
Carnosic Acid | 📋 | | | | 31356939 | Interaction mechanism of carnosic acid against glycosidase (α-amylase and α-glucosidase) |
Casein Protein | 📋 | ✍ | ⛔ | | 35948437 | Dairy Milk Casein and Whey Proteins Differentially Alter the Postprandial Lipidome in Persons with Prediabetes: A Comparative Lipidomics Study |
Cheese | 📋 | | ⛔ | | 35503897 | Cheese Intake is Inversely Associated with LDL Cholesterol in Young Children |
Chili Pepper | 📋 | | ⛔ | | 36907948 | Enhanced hypoglycemic bioactivity via RAS/Raf-1/MEK/ERK signaling pathway by combining capsaicin and QUERCETIN from chili peppers |
Citron | 📋 | | ⛔ | | 34710667 | Structurally diverse biflavonoids from the fruits of Citrus medica L. var. sarcodactylis Swingle and their hypolipidemic and immunosuppressive activities |
Clove Essential Oil | 📋 | | ⛔ | | 35212917 | Syzygium aromaticum bud (clove) essential oil is a novel and safe aldose reductase inhibitor: in silico, in vitro, and in vivo evidence |
Conjugated Linoleic Acid | 📋 | ✍ | ⛔ | | 36438733 | The effects of conjugated linoleic acid supplementation on lipid profile in adults: A systematic review and dose-response meta-analysis |
Corn | 📋 | | ⛔ | | 30204921 | Corn Oil Lowers Plasma Cholesterol Compared with Coconut Oil in Adults with Above-Desirable Levels of Cholesterol in a Randomized Crossover Trial |
Costus | 📋 | ✍ | ⛔ | | 33069202 | The anti-diabetic effect of some plant extracts against Streptozotocin - induced diabetes type 2 in male albino rats |
Creatine | 📋 | ✍ | ⛔ | | 12969151 | Creatine Supplementation Decreases Homocysteine in an Animal Model of Uremia |
Cumin | 📋 | | ⛔ | | 34328087 | Supplementation of cumin seed powder prevents oxidative stress, hyperlipidemia and non-alcoholic fatty liver in high fat diet fed rats |
Dairy | 📋 | | | | 35623880 | Urate-lowering effect of calcium supplementation: Analyses of a randomized controlled trial |
Delphinidin | 📋 | | | | 34281481 | Delphinidin-3-sambubioside from Hibiscus sabdariffa. L attenuates hyperlipidemia in high fat diet-induced obese rats and oleic acid-induced steatosis in HepG2 cells |
Deodar Cedar | 📋 | | | | 35325515 | Attenuation of cisplatin induced myelosuppression by methanol extract of Cedrus deodara in wistar rats |
Diallyl Trisulfide | 📋 | | | | 31927886 | Diallyl Trisulfide Inhibits Platelet Aggregation through the Modification of Sulfhydryl Groups |
Dihydroartemisinin | 📋 | | | | 34847494 | Dihydroartemisinin improves hypercholesterolemia in ovariectomized mice via enhancing vectorial transport of cholesterol and bile acids from blood to bile |
Dill | 📋 | | ⛔ | | 30668411 | Medicinal plants in treatment of hypertriglyceridemia: A review based on their mechanisms and effectiveness |
DIM | 📋 | ✍ | ⛔ | | 35151647 | Diindolylmethane ameliorates platelet aggregation and thrombosis: In silico, in vitro, and in vivo studies |
Eleuthero | 📋 | ✍ | ⛔ | | 17612394 | Reduction of Urate Crystal-Induced Inflammation by Root Extracts From Traditional Oriental Medicinal Plants: Elevation of Prostaglandin D2 Levels |
Equol | 📋 | ✍ | ⛔ | | 34749871 | [Lipids-lowering effects of equol on low density lipoprotein receptor knockout hamsters] |
Essential Oils | 📋 | | ⛔ | | 38003691 | Antioxidant and Hypoglycemic Potential of Essential Oils in Diabetes Mellitus and Its Complications |
Eucalyptus | 📋 | ✍ | ⛔ | | 34685597 | 1,8-Cineole Affects Agonists-Induced Platelet Activation, Thrombus Formation and Haemostasis |
Fat | 📋 | | | | 35617705 | Partial Replacement of High-Fat Diet with Beef Tallow Attenuates Dyslipidemia and Endoplasmic Reticulum Stress in db/ db Mice |
Fennel Essential Oil | 📋 | ✍ | ⛔ | | 30417995 | Health Benefits of Fennel, Rosemary Volatile Oils and their Nano-Forms in Dyslipidemic Rat Model |
Fish | 📋 | | ⛔ | | 38263170 | Dietary patterns derived by reduced rank regression are associated with lipid disorders among Korean adults: a cross-sectional analysis |
Fluted Gourd | 📋 | | | | 34987254 | Anti-hyperlipidemic and antioxidant potentials of aqueous leaf extract of Telfairia occidentalis (fluted pumpkin) in male Sprague-Dawley rats |
Fruits | 📋 | | | | 31004140 | The effects of fruit consumption in patients with hyperuricaemia or gout |
GABA | 📋 | ✍ | ⛔ | | 38256069 | Anti-Obesity Effects of GABA in C57BL/6J Mice with High-Fat Diet-Induced Obesity and 3T3-L1 Adipocytes |
Galangin | 📋 | | | | 29952676 | Galangin, a dietary flavonoid, ameliorates hyperglycaemia and lipid abnormalities in rats with streptozotocin-induced hyperglycaemia |
Gamma-Linolenic Acid | 📋 | ✍ | ⛔ | | 2848532 | Suppression of monosodium urate crystal-induced acute inflammation by diets enriched with gamma-linolenic acid and eicosapentaenoic acid |
Ganoderic Acid | 📋 | | | | 32686808 | Ganoderic acid A from Ganoderma lucidum ameliorates lipid metabolism and alters gut microbiota composition in hyperlipidemic mice fed a high-fat diet |
Geranium | 📋 | | | | 35170422 | Effect of Pelargonium graveolens on Glucose Metabolism in Streptozotocin-Induced Diabetic Rats |
Giloy | 📋 | ✍ | ⛔ | | 35673460 | Integrated omics analysis revealed the Tinospora cordifolia intervention modulated multiple signaling pathways in hypertriglyceridemia patients-a pilot clinical trial |
Ginger Essential Oil | 📋 | ✍ | | | 28638882 | POSSIBLE HYPOCHOLESTEROLEMIC EFFECT OF GINGER AND ROSEMARY OILS IN RATS |
Ginkgetin | 📋 | | | | 38334198 | Ginkgetin effectively mitigates collagen and AA-induced platelet activation via PLCγ2 but not cyclic nucleotide-dependent pathway in human |
Glucosamine | 📋 | ✍ | ⛔ | | 37329549 | Glucosamine effects on platelet aggregation of type 2 diabetes mellitus patients: in vitro assays |
Grape Seed Oil | 📋 | | ⛔ | | 31117552 | Hypocholesterolemic Effects of Expeller-Pressed and Solvent-Extracted Fruit Seed Oils and Defatted Pomegranate Seed Meals |
Grapefruit Essential Oil | 📋 | ✍ | ⛔ | | 32760938 | Dietary citrus peel essential oil ameliorates hypercholesterolemia and hepatic steatosis by modulating lipid and cholesterol homeostasis |
Honeysuckle | 📋 | | ⛔ | | 35550649 | Blue honeysuckle extracts retarded starch digestion by inhibiting glycosidases and changing the starch structure |
Horny Goat Weed | 📋 | ✍ | ⛔ | | 32014688 | Epimedium polysaccharides attenuates hematotoxicity by reducing oxidative stress and enhancing immune function in mice model of benzene-induced bone marrow failure |
Hyperoside | 📋 | | | | 36115306 | Structure-activity relationships and the underlying mechanism of α-amylase inhibition by hyperoside and quercetin: Multi-spectroscopy and molecular docking analyses |
Isorhamnetin | 📋 | | | | 32918994 | Network pharmacology analysis and experimental validation to explore the mechanism of sea buckthorn flavonoids on hyperlipidemia |
Jackfruit | 📋 | | ⛔ | | 35335251 | Inhibitory Effect of Polyphenols from the Whole Green Jackfruit Flour against α-Glucosidase, α-Amylase, Aldose Reductase and Glycation at Multiple Stages and Their Interaction: Inhibition Kinetics and Molecular Simulations |
Kale | 📋 | | | | 34432833 | Kale supplementation during high fat feeding improves metabolic health in a mouse model of obesity and insulin resistance |
L-Ornithine | 📋 | ✍ | ⛔ | | 37707596 | Combination of tea catechins and ornithine effectively activates the urea cycle: an in vitro and human pilot study |
Laminaria | 📋 | ✍ | ⛔ | | 37702045 | Fucogalactan Sulfate (FS) from Laminaria japonica Regulates Lipid Metabolism in Diet-Induced Humanized Dyslipidemia Mice via an Intestinal FXR-FGF19-CYP7A1/CYP8B1 Pathway |
Lavender Essential Oil | 📋 | ✍ | ⛔ | | 15636172 | Novel antiplatelet and antithrombotic activities of essential oil from Lavandula hybrida Reverchon "grosso" |
Lemon Essential Oil | 📋 | ✍ | ⛔ | | 32760938 | Dietary citrus peel essential oil ameliorates hypercholesterolemia and hepatic steatosis by modulating lipid and cholesterol homeostasis |
Lettuce | 📋 | | ⛔ | | 34261489 | The acute effect of incorporating lettuce or watercress into a moderately high-fat meal on postprandial lipid, glycemic response, and plasma inflammatory cytokines in healthy young men: a randomized crossover trial |
Lime Essential Oil | 📋 | ✍ | ⛔ | | 31500259 | Lime ( Citrus aurantifolia (Christm.) Swingle) Essential Oils: Volatile Compounds, Antioxidant Capacity, and Hypolipidemic Effect |
Limonin | 📋 | | | | 38375746 | Limonin alleviates high-fat diet-induced dyslipidemia by regulating the intestinal barrier via the microbiota-related ILC3-IL22-IL22R pathway |
Linalool | 📋 | | ⛔ | | 35565791 | Olfactory Stimulation with Volatile Aroma Compounds of Basil ( Ocimum basilicum L.) Essential Oil and Linalool Ameliorates White Fat Accumulation and Dyslipidemia in Chronically Stressed Rats |
Lion's Mane Mushrooms | 📋 | ✍ | ⛔ | | 33822499 | Evaluation of In Vitro Antioxidant and Antihyperglycemic Activities of Extracts from the Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes) |
Lupeol | 📋 | | | | 34141163 | Alleviating effects of lupeol on postprandial hyperglycemia in diabetic mice |
Marjoram | 📋 | | ⛔ | | 32158345 | Anti-Hypolipidemic and Anti-Oxidative Effects of Hydroalcoholic Extract of Origanum majorana on the Hepatosteatosis Induced with High-Fat Diet in Rats |
Mastic | 📋 | ✍ | ⛔ | | 35691258 | Efficacy of a standardized herbal product from Pistacia atlantica subsp. Kurdica in type 2 diabetic patients with hyperlipidemia: A triple-blind randomized clinical trial |
Milk | 📋 | | ⛔ | | 35948437 | Dairy Milk Casein and Whey Proteins Differentially Alter the Postprandial Lipidome in Persons with Prediabetes: A Comparative Lipidomics Study |
Motherwort | 📋 | ✍ | ⛔ | | 36746759 | Activating Blood Circulation, Anti-inflammatory and Diuretic Effects of Leonurus japonicus Extract on a Rat Model of Trauma Blood Stasis and Its Phytochemical Profiling |
Mucuna Pruriens | 📋 | ✍ | ⛔ | | 36458299 | Hypolipidemic and antioxidant effects of vegetal milk produced with Mucuna pruriens L. seed in rats fed a high-fat diet |
MUFA | 📋 | | ⛔ | | 16969381 | Effects of hazelnut-enriched diet on plasma cholesterol and lipoprotein profiles in hypercholesterolemic adult men |
Mushrooms | 📋 | | ⛔ | | 36904079 | An Assessment of Mushroom Consumption on Cardiometabolic Disease Risk Factors and Morbidities in Humans: A Systematic Review |
Myrtle Essential Oil | 📋 | ✍ | ⛔ | | 15234770 | Hypoglycaemic effects of myrtle oil in normal and alloxan-diabetic rabbits |
Neferine | 📋 | | | | 38549521 | Neferine Targeted the NLRC5/NLRP3 Pathway to Inhibit M1-type Polarization and Pyroptosis of Macrophages to Improve Hyperuricemic Nephropathy |
Neohesperidin | 📋 | | | | 28554169 | Neohesperidin Exerts Lipid-Regulating Effects in vitro and in vivo via Fibroblast Growth Factor 21 and AMP-Activated Protein Kinase/Sirtuin Type 1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α Signaling Axis |
Oleanolic Acid | 📋 | | | | 37520251 | Oleanolic acid and moderate drinking increase the pancreatic GLP-1R expression of the β-cell mass deficiency induced hyperglycemia |
Olive | 📋 | ✍ | ⛔ | | 38089061 | The antihyperlipidemic effect of a combined supplement of standardized dry extracts of amla ( Emblica officinalis), walnut ( Juglans regia), olive ( Olea europaea) and red yeast rice ( Monascus purpureus) powder: Reduction in circulatory low-density lipoprotein-cholesterol (LDL-C) and remnant cholesterol (RC) levels in patients with hypercholesterolemia |
Orange Essential Oil | 📋 | ✍ | ⛔ | | 32760938 | Dietary citrus peel essential oil ameliorates hypercholesterolemia and hepatic steatosis by modulating lipid and cholesterol homeostasis |
Parsley | 📋 | | ⛔ | | 27069727 | Hepatoprotective effects of parsley, basil, and chicory aqueous extracts against dexamethasone-induced in experimental rats |
Parthenolide | 📋 | | | | 36234807 | First Discovery of Cholesterol-Lowering Activity of Parthenolide as NPC1L1 Inhibitor |
Pear | 📋 | | ⛔ | | 12952433 | Apple and pear peel and pulp and their influence on plasma lipids and antioxidant potentials in rats fed cholesterol-containing diets |
Pectin | 📋 | ✍ | ⛔ | | 33897940 | Dietary Fiber: An Opportunity for a Global Control of Hyperlipidemia |
Peppermint Essential Oil | 📋 | ✍ | ⛔ | | 28922713 | Peppermint essential oil alleviates hyperglycemia caused by streptozotocin- nicotinamide-induced type 2 diabetes in rats |
Phosphatidylcholine | 📋 | ✍ | ⛔ | | 16002808 | Choline supplemented as phosphatidylcholine decreases fasting and postmethionine-loading plasma homocysteine concentrations in healthy men |
Pine Nut | 📋 | | ⛔ | | 34261569 | Nut intake and hyperuricemia risk in young adults |
Protein | 📋 | ✍ | ⛔ | | 37876152 | High Plant Protein Diet Ameliorated Hepatic Lipid Accumulation Through the Modulation of Gut Microbiota |
Rhubarb | 📋 | | ⛔ | | 37808167 | Mechanism of rhubarb in the treatment of hyperlipidemia: A recent review |
Rosehip Seed Oil | 📋 | | ⛔ | | 32992796 | Sea Buckthorn and Rosehip Oils with Chokeberry Extract to Prevent Hypercholesterolemia in Mice Caused by a High-Fat Diet In Vivo |
Rye | 📋 | | ⛔ | | 37898434 | Effects of Wholegrain Compared to Refined Grain Intake on Cardiometabolic Risk Markers, Gut Microbiota and Gastrointestinal Symptoms in Children: A Randomized Crossover Trial |
Salvianolic Acid | 📋 | | | | 33847919 | Anti-thrombotic activity of phenolic acids obtained from Salvia miltiorrhiza f. alba in TNF-α-stimulated endothelial cells via the NF-κB/JNK/p38 MAPK signaling pathway |
Sardine | 📋 | | ⛔ | | 36860672 | Cardiovascular and lipid-lowering effects of a marine lipoprotein extract in a high-fat diet-induced obesity mouse model |
Schisandrins | 📋 | | | | 33961837 | UGT1A1 dysfunction increases liver burden and aggravates hepatocyte damage caused by long-term bilirubin metabolism disorder |
Scutellarin | 📋 | | | | 29172017 | Scutellarin Prevents Nonalcoholic Fatty Liver Disease (NAFLD) and Hyperlipidemia via PI3K/AKT-Dependent Activation of Nuclear Factor (Erythroid-Derived 2)-Like 2 (Nrf2) in Rats |
Sesamolin | 📋 | | | | 35396857 | Comparative effects of sesame lignans (sesamin, sesamolin, and sesamol) on oxidative stress and lipid metabolism in steatosis HepG2 cells |
Shallot | 📋 | | ⛔ | | 36274534 | The effect of Allium hirtifolium bulb on serum lipid profile in adult patients with hyperlipidemia: A randomized double-blind placebo-controlled clinical trial |
Sodium Bicarbonate | 📋 | ✍ | ⛔ | | 36699087 | Clinical effectiveness of sodium bicarbonate therapy on mortality for septic patients with acute moderate lactic acidosis |
Soybean Oil | 📋 | | ⛔ | | 22205583 | Effect of soybean oil on atherogenic metabolic risks associated with estrogen deficiency in ovariectomized rats: dietary soybean oil modulate atherogenic risks in overiectomized rats |
Stigmasterol | 📋 | | | | 31759199 | Stigmasterol stimulates transintestinal cholesterol excretion independent of liver X receptor activation in the small intestine |
Sunflower | 📋 | | ⛔ | | 34194097 | Lipid profile of hyperlipidemic males after supplementation of multigrain bread containing sunflower ( Helianthus annuus) seed flour |
Sunflower Oil | 📋 | ✍ | ⛔ | | 37627620 | Ozonated Sunflower Oil Exerted Potent Anti-Inflammatory Activities with Enhanced Wound Healing and Tissue Regeneration Abilities against Acute Toxicity of Carboxymethyllysine in Zebrafish with Improved Blood Lipid Profile |
Tea Polyphenols | 📋 | | | | 36444016 | Tea polyphenol and epigallocatechin gallate ameliorate hyperlipidemia via regulating liver metabolism and remodeling gut microbiota |
Tea Polysaccharides | 📋 | | | | 25820466 | Pu-erh tea polysaccharides decrease blood sugar by inhibition of α-glucosidase activity in vitro and in mice |
Thyme Essential Oil | 📋 | | ⛔ | | 33995021 | Chemical Composition, Antioxidant Potential, and Blood Glucose Lowering Effect of Aqueous Extract and Essential Oil of Thymus Serrulatus Hochst. Ex Benth |
Turnip | 📋 | | ⛔ | | 34886781 | Aqueous Extract of Brassica rapa Exerts Antihyperglycemic Activity in Streptozotocin-induced Diabetic Rats |
UDCA | 📋 | ✍ | ⛔ | | 38085723 | Evaluation of therapeutic effect of oral Ursodeoxycholic Acid on indirect hyperbilirubinemia in term neonates undergoing phototherapy: A randomized controlled clinical trial |
Urolithins | 📋 | | | | 33158257 | Antihyperuricemic Effect of Urolithin A in Cultured Hepatocytes and Model Mice |
Vegetables | 📋 | | | | 36904173 | Eating Vegetables First Regardless of Eating Speed Has a Significant Reducing Effect on Postprandial Blood Glucose and Insulin in Young Healthy Women: Randomized Controlled Cross-Over Study |
Vitamin A | 📋 | ✍ | ⛔ | | 33364042 | Combined effect of high-dose vitamin A, vitamin E supplementation, and zinc on adult patients with diabetes: A randomized trial |
Vitamin B2 | 📋 | ✍ | ⛔ | | 35635046 | Successful Treatment of Tenofovir Alafenamide-Induced Lactic Acidosis: A Case Report |
Vitamin B5 | 📋 | ✍ | ⛔ | | 10960503 | Effect of pantothenic acid on hippurate formation in sodium benzoate-treated HepG2 cells |
Vitamin B7 | 📋 | ✍ | ⛔ | | 36047096 | Dietary High-Dose Biotin Intake Activates Fat Oxidation and Hepatic Carnitine Palmitoyltransferase in Rat |
Vitamin B8 | 📋 | ✍ | ⛔ | | 38137721 | Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial |
Vitamin K | 📋 | ✍ | ⛔ | | 33454929 | A critical review of the effects of vitamin K on glucose and lipid homeostasis: its potential role in the prevention and management of type 2 diabetes |
Vitamin K1 | 📋 | ✍ | ⛔ | | 29175667 | Vitamin K1 inversely correlates with glycemia and insulin resistance in patients with type 2 diabetes (T2D) and positively regulates SIRT1/AMPK pathway of glucose metabolism in liver of T2D mice and hepatocytes cultured in high glucose |
Wasabi | 📋 | | ⛔ | | 36360048 | Wasabi ( Eutrema japonicum) Reduces Obesity and Blood Pressure in Diet-Induced Metabolic Syndrome in Rats |
Wheat | 📋 | | ⛔ | | 35408659 | The Hypolipidemic and Antioxidant Activity of Wheat Germ and Wheat Germ Protein in High-Fat Diet-Induced Rats |
Wood Ear Mushrooms | 📋 | | ⛔ | | 34505615 | Hypoglycemic effects of Auricularia auricula polysaccharides on high fat diet and streptozotocin-induced diabetic mice using metabolomics analysis |
Yerba Mate | 📋 | ✍ | ⛔ | | 38327997 | Ilex paraguariensis A.St.-Hil. improves lipid metabolism in high-fat diet-fed obese rats and suppresses intracellular lipid accumulation in 3T3-L1 adipocytes via the AMPK-dependent and insulin signaling pathways |
Zingerone | 📋 | | | | 25558849 | Antihyperlipidaemic, antihypertrophic, and reducing effects of zingerone on experimentally induced myocardial infarcted rats |